The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease.
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CCSVI and MS: no meaning, no factSoft materials to treat central nervous system injuries: evaluation of the suitability of non-mammalian fibrin gelsBreaking boundaries-coagulation and fibrinolysis at the neurovascular interfaceFingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapyThe Inflammatory Role of Platelets: Translational Insights from Experimental Studies of Autoimmune DisordersProcessing of Factor XII during Inflammatory ReactionsPesticides, microglial NOX2, and Parkinson's diseaseLesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?NIH workshop report on the trans-agency blood-brain interface workshop 2016: exploring key challenges and opportunities associated with the blood, brain and their interface.Inflammation and Gliomagenesis: Bi-Directional Communication at Early and Late Stages of Tumor Progression.Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMβ2 leukocyte integrin receptorA novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease miceMacrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.Enhancement of fibrinogen-triggered pro-coagulant activation of monocytes in vitro by matrix metalloproteinase-9.Early detection of thrombin activity in neuroinflammatory disease.Importance of oligodendrocyte protection, BBB breakdown and inflammation for remyelination.A T cell-binding fragment of fibrinogen can prevent autoimmunity.Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damageIdentification of biomarkers for diagnosis and progression of MS by MALDI-TOF mass spectrometry.Fibrinogen signal transduction in the nervous system.Factor XIII activity mediates red blood cell retention in venous thrombi.Plasmin deficiency leads to fibrin accumulation and a compromised inflammatory response in the mouse brainThe role of microglia in human disease: therapeutic tool or target?Matrix metalloproteinase-12 deficiency ameliorates the clinical course and demyelination in Theiler's murine encephalomyelitis.In vivo imaging of the neurovascular unit in CNS disease.Effects of caspase-1 knockout on chronic neural recording quality and longevity: insight into cellular and molecular mechanisms of the reactive tissue response.The role of antigen presenting cells in multiple sclerosis.The blood-brain barrier in health and disease.Proteomic analysis of cerebrospinal fluid in a fulminant case of multiple sclerosis.Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.Ablation of matrix metalloproteinase-9 gene decreases cerebrovascular permeability and fibrinogen deposition post traumatic brain injury in mice.Heterozygosity for fibrinogen results in efficient resolution of kidney ischemia reperfusion injury.Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo.Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis.Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the α5β1 integrin.Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation.Evaluation of fibrinogen self-assembly: role of its αC region.Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence.Thrombin drives tumorigenesis in colitis-associated colon cancerColitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen
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The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The fibrin-derived gamma377-39 ...... ous system autoimmune disease.
@ast
The fibrin-derived gamma377-39 ...... ous system autoimmune disease.
@en
type
label
The fibrin-derived gamma377-39 ...... ous system autoimmune disease.
@ast
The fibrin-derived gamma377-39 ...... ous system autoimmune disease.
@en
prefLabel
The fibrin-derived gamma377-39 ...... ous system autoimmune disease.
@ast
The fibrin-derived gamma377-39 ...... ous system autoimmune disease.
@en
P2093
P2860
P356
P1476
The fibrin-derived gamma377-39 ...... ous system autoimmune disease.
@en
P2093
Jay L Degen
Matthew J Flick
Ryan A Adams
Shoana L Sikorski
Tal Nuriel
P2860
P304
P356
10.1084/JEM.20061931
P407
P577
2007-03-05T00:00:00Z