PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors.

PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors.

Item
http://www.wikidata.org/entity/Q36268182
Antiangiogenic and Antitumor Activities of Aflibercept, a Soluble VEGF Receptor-1 and -2, in a Mouse Model of Hepatocellular Carcinoma.Notch4+ cancer stem-like cells promote the metastatic and invasive ability of melanoma.Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism.Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis.Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia.PPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic targetInhibition of hypoxia-inducible factor via upregulation of von Hippel-Lindau protein induces "angiogenic switch off" in a hepatoma mouse model.Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning.Dual roles of endothelial FGF-2-FGFR1-PDGF-BB and perivascular FGF-2-FGFR2-PDGFRβ signaling pathways in tumor vascular remodeling.Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy.
P2860

PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors.

Item
http://www.wikidata.org/entity/Q36268182
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
PlGF-induced VEGFR1-dependent ...... ance to Dll4-Notch inhibitors.
@ast
PlGF-induced VEGFR1-dependent ...... ance to Dll4-Notch inhibitors.
@en
type
label
PlGF-induced VEGFR1-dependent ...... ance to Dll4-Notch inhibitors.
@ast
PlGF-induced VEGFR1-dependent ...... ance to Dll4-Notch inhibitors.
@en
prefLabel
PlGF-induced VEGFR1-dependent ...... ance to Dll4-Notch inhibitors.
@ast
PlGF-induced VEGFR1-dependent ...... ance to Dll4-Notch inhibitors.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
PlGF-induced VEGFR1-dependent ...... ance to Dll4-Notch inhibitors.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932