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Targeting cardiac mast cells: pharmacological modulation of the local renin-angiotensin systemSoluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive ratsRenal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity.Rationale for combining a direct renin inhibitor with other renin- angiotensin system blockers. Focus on aliskiren and combinations.Multiphoton imaging of renal regulatory mechanisms.Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents.A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link?Recent advances involving the renin-angiotensin systemRole of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analysesHigh salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension.First-line treatment of hypertension: critical appraisal of potential role of aliskiren and hydrochlorothiazide in a fixed combination.Structural libraries of protein models for multiple species to understand evolution of the renin-angiotensin system.Receptor-mediated nonproteolytic activation of prorenin and induction of TGF-β1 and PAI-1 expression in renal mesangial cells.Novel roles of intracrine angiotensin II and signalling mechanisms in kidney cells.Renal dopamine and angiotensin II receptor signaling in age-related hypertension.Prorenin anno 2008.The collecting duct is the major source of prorenin in diabetesOral direct renin inhibition: premise, promise, and potential limitations of a new antihypertensive drug.Renin: friend or foe?Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells.Renin release.Spectroscopic and Docking Studies on the Binding of Liquiritigenin with Hyaluronidase for Antiallergic Mechanism.Aliskiren-hydrochlorothiazide combination for the treatment of hypertension.Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapyNew frontiers in the intrarenal Renin-Angiotensin system: a critical review of classical and new paradigms.Prorenin and the (pro)renin receptor: binding kinetics, signalling and interaction with aliskiren.Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney.Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria.Renin-angiotensin-aldosterone system blockade in diabetes: role of direct renin inhibitors.Managing cardiovascular and renal risk: the potential of direct renin inhibition.The (pro)renin receptor in health and disease.Recent advances in tissue (pro)renin imaging.Aliskiren: beyond blood pressure reduction.New roles for renin and prorenin in heart failure and cardiorenal crosstalk.The role of renin inhibition in treating the hypertensive patient with diabetes: a summary of preclinical and clinical evidence.Inhibition of renin and the (pro)renin receptor system.Is the renin-angiotensin system actually hypertensive?Review of companies and drug classes in the 2007-2011 antihypertensive patent literature.Update on role of direct renin inhibitor in diabetic kidney disease.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Renin, prorenin and the putative (pro)renin receptor.
@ast
Renin, prorenin and the putative (pro)renin receptor.
@en
type
label
Renin, prorenin and the putative (pro)renin receptor.
@ast
Renin, prorenin and the putative (pro)renin receptor.
@en
prefLabel
Renin, prorenin and the putative (pro)renin receptor.
@ast
Renin, prorenin and the putative (pro)renin receptor.
@en
P1433
P1476
Renin, prorenin and the putative (pro)renin receptor.
@en
P2093
A H Jan Danser
Jaap Deinum
P304
P356
10.1161/01.HYP.0000186329.92187.2E
P407
P577
2005-09-26T00:00:00Z