Pharmacogenetics of folate-related drug targets in cancer treatment. - Wikidata - awgldk - TriplyDB

Pharmacogenetics of folate-related drug targets in cancer treatment.

Pharmacogenetics of folate-related drug targets in cancer treatment.

http://www.wikidata.org/entity/Q36278007

about

Characterizing the network of drugs and their affected metabolic subpathways Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer.Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304).Genetic and environmental determinants of plasma total homocysteine levels: impact of population-wide folate fortification.High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients.A comparison of approaches for association studies of polymorphisms and colorectal cancer risk.Folate Intake, MTHFR Polymorphisms, and the Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis Clinical implications of genetic polymorphisms on stomach cancer drug therapy.Predictors of survival and toxicity in patients on adjuvant therapy with 5-fluorouracil for colorectal cancer Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines Controversial roles of methylenetetrahydrofolate reductase polymorphisms and folate in breast cancer disease.Pharmacogenomics of fluorouracil -based chemotherapy toxicity.Alterations in the expression pattern of MTHFR, DHFR, TYMS, and SLC19A1 genes after treatment of laryngeal cancer cells with high and low doses of methotrexate.Methylenetetrahydrofolate reductase and thymidylate synthase genotypes modify oral mucositis severity following hematopoietic stem cell transplantation.Impact of acute lymphoblastic leukemia therapy on attention and working memory in children.Association of folate transporter SLC19A1 polymorphisms with the outcome of multiple myeloma after chemotherapy and tandem autologous transplantation.

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P2860

Pharmacogenetics of folate-related drug targets in cancer treatment.

http://www.wikidata.org/entity/Q36278007

description

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Pharmacogenetics of folate-related drug targets in cancer treatment.

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Pharmacogenetics of folate-related drug targets in cancer treatment.

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Pharmacogenetics of folate-related drug targets in cancer treatment.

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Pharmacogenetics of folate-related drug targets in cancer treatment.

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Pharmacogenomics

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Pharmacogenetics of folate-related drug targets in cancer treatment.

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Alanna Boynton

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Cornelia M Ulrich

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Kim Robien

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P2860

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defec

Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults

The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia

A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil

A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells

Folic acid: nutritional biochemistry, molecular biology, and role in disease processes.

Update on antifolate drugs targets.

Biological and clinical implications of the MTHFR C677T polymorphism.

The role of folic acid and Vitamin B12 in genomic stability of human cells.

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673-689

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scholarly article

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10.2217/14622416.6.7.673

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