Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation. - Wikidata - awgldk - TriplyDB

Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation.

Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation.

http://www.wikidata.org/entity/Q36280608

about

Structure, function and regulation of CSB: a multi-talented gymnast Accessorizing the human mitochondrial transcription machinery Double-stranded DNA-dependent ATPase Irc3p is directly involved in mitochondrial genome maintenance The cockayne syndrome B protein is essential for neuronal differentiation and neuritogenesis ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function.NAP1L1 accelerates activation and decreases pausing to enhance nucleosome remodeling by CSB CSB interacts with SNM1A and promotes DNA interstrand crosslink processing Blinded by the UV light: how the focus on transcription-coupled NER has distracted from understanding the mechanisms of Cockayne syndrome neurologic disease DNA repair mechanisms in dividing and non-dividing cells.The sequence-specific transcription factor c-Jun targets Cockayne syndrome protein B to regulate transcription and chromatin structure.Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome The mitochondrial nucleoid: integrating mitochondrial DNA into cellular homeostasis Mitochondrial deficiency in Cockayne syndrome.Multiple interaction partners for Cockayne syndrome proteins: implications for genome and transcriptome maintenance Genetic syndromes caused by mutations in epigenetic genes.Mitochondrial dysfunction: a neglected component of skin diseases.The role of DNA base excision repair in brain homeostasis and disease.Regulation of RNA polymerase II-mediated transcriptional elongation: Implications in human disease.Cockayne syndrome: Clinical features, model systems and pathways.Mechanistic and biological considerations of oxidatively damaged DNA for helicase-dependent pathways of nucleic acid metabolism.Lack of XPC leads to a shift between respiratory complexes I and II but sensitizes cells to mitochondrial stress.Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells.

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P2860

Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation.

http://www.wikidata.org/entity/Q36280608

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

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2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Human Cockayne syndrome B prot ...... es transcriptional elongation.

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Human Cockayne syndrome B prot ...... es transcriptional elongation.

@en

type

label

Human Cockayne syndrome B prot ...... es transcriptional elongation.

@ast

Human Cockayne syndrome B prot ...... es transcriptional elongation.

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prefLabel

Human Cockayne syndrome B prot ...... es transcriptional elongation.

@ast

Human Cockayne syndrome B prot ...... es transcriptional elongation.

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Nucleic Acids Research

P1476

Human Cockayne syndrome B prot ...... es transcriptional elongation.

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P2093

Brian R Berquist

http://www.w3.org/2001/XMLSchema#string

Chandrika Canugovi

http://www.w3.org/2001/XMLSchema#string

David M Wilson

http://www.w3.org/2001/XMLSchema#string

Peter Sykora

http://www.w3.org/2001/XMLSchema#string

Vilhelm A Bohr

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P2860

Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome

Functional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB protein

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro

Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II

Cockayne syndrome group B protein enhances elongation by RNA polymerase II

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

TEFM (c17orf42) is necessary for transcription of human mtDNA

Molecular analysis of mutations in the CSB (ERCC6) gene in patients with Cockayne syndrome

Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B

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8392-8405

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10.1093/NAR/GKS565

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17

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40

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2012-06-28T00:00:00Z

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228087364

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22743267

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3458532

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