Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin.
about
Identification of transglutaminase-mediated deamidation sites in a recombinant alpha-gliadin by advanced mass-spectrometric methodologiesThe intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminaseSpecificity of tissue transglutaminase explains cereal toxicity in celiac diseaseThe HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responsesA role for tissue transglutaminase in alpha-gliadin peptide cytotoxicityIgA antibodies of coeliac disease patients recognise a dominant T cell epitope of A-gliadinAlpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopesCeliac disease: quantity mattersT-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac diseaseHighly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac diseaseCoeliac disease and gluten-related disorders in childhoodB cell epitopes of gliadin.A tertiary twist to the transglutaminase taleA catalogue of Triticum monococcum genes encoding toxic and immunogenic peptides for celiac disease patientsThe preferred substrates for transglutaminase 2 in a complex wheat gluten digest are Peptide fragments harboring celiac disease T-cell epitopesA universal approach to eliminate antigenic properties of alpha-gliadin peptides in celiac diseaseDiagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology.HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac diseaseCeliac disease: how complicated can it get?Pathophysiology of celiac diseaseCeliac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variationThe immune recognition of gluten in coeliac disease.Pathogenesis of coeliac disease: implications for treatmentMolecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells.Coeliac disease: dissecting a complex inflammatory disorder.Wheat.Epithelial transport of immunogenic and toxic gliadin peptides in vitro.An immunodominant DQ8 restricted gliadin peptide activates small intestinal immune response in in vitro cultured mucosa from HLA-DQ8 positive but not HLA-DQ8 negative coeliac patients.Investigation of the putative immunodominant T cell epitopes in coeliac disease.Intestinal T cell responses to gluten peptides are largely heterogeneous: implications for a peptide-based therapy in celiac disease.Gliadin activates HLA class I-restricted CD8+ T cells in celiac disease intestinal mucosa and induces the enterocyte apoptosis.Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules.Brachypodium distachyon as a model for defining the allergen potential of non-prolamin proteins.Immunomodulatory strategies for celiac disease.Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic Abo Dq8 transgenic mice.Insights in the laboratory diagnosis of celiac disease.Celiac disease: pathogenesis of a model immunogenetic disease.Consumption of gluten with gluten-degrading enzyme by celiac patients: a pilot-study.Antigen presentation in celiac disease.In vitro models for gluten toxicity: relevance for celiac disease pathogenesis and development of novel treatment options.
P2860
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P2860
Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Small intestinal T cells of ce ...... al pepsin fragment of gliadin.
@ast
Small intestinal T cells of ce ...... al pepsin fragment of gliadin.
@en
type
label
Small intestinal T cells of ce ...... al pepsin fragment of gliadin.
@ast
Small intestinal T cells of ce ...... al pepsin fragment of gliadin.
@en
prefLabel
Small intestinal T cells of ce ...... al pepsin fragment of gliadin.
@ast
Small intestinal T cells of ce ...... al pepsin fragment of gliadin.
@en
P2093
P2860
P356
P1476
Small intestinal T cells of ce ...... al pepsin fragment of gliadin.
@en
P2093
J W Drijfhout
K E Lundin
L M Mearin
L M Sollid
P A van Veelen
W E Benckhuijsen
P2860
P304
10050-10054
P356
10.1073/PNAS.95.17.10050
P407
P577
1998-08-01T00:00:00Z