Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. - Wikidata - awgldk - TriplyDB

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

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Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8 Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis Ubc13: the Lys63 ubiquitin chain building machine E2 enzymes: more than just middle men Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases Role of E2-Ub-conjugating enzymes during skeletal muscle atrophy RBR E3 ubiquitin ligases: new structures, new insights, new questions RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination Atomic structure of the APC/C and its mechanism of protein ubiquitination.Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy A conserved asparagine has a structural role in ubiquitin-conjugating enzymes Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism Structure of the human Parkin ligase domain in an autoinhibited state Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3 Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 Molecular basis for specificity of the Met1-linked polyubiquitin signal Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase Perilous journey: a tour of the ubiquitin-proteasome system Crystal Structure of a Ube2S-Ubiquitin Conjugate A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125 Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.Changes in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response.Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.Systematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeast

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Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

http://www.wikidata.org/entity/Q36291328

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Structure of an E3:E2~Ub compl ...... ared among RING/U-box ligases.

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Structure of an E3:E2~Ub compl ...... ared among RING/U-box ligases.

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Structure of an E3:E2~Ub compl ...... ared among RING/U-box ligases.

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Structure of an E3:E2~Ub compl ...... ared among RING/U-box ligases.

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Structure of an E3:E2~Ub compl ...... ared among RING/U-box ligases.

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Structure of an E3:E2~Ub compl ...... ared among RING/U-box ligases.

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J.MOLCEL.2012.07.001

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Structure of an E3:E2~Ub compl ...... hared among RING/U-box ligases

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Kyle A Nordquist

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Peter J Littlefield

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Peter S Brzovic

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Rachel E Klevit

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Sarah E Soss

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Walter J Chazin

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P2860

Structural and functional characterization of the monomeric U-box domain from E4B

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

Caretaker Brca1: keeping the genome in the straight and narrow.

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

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933-942

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10.1016/J.MOLCEL.2012.07.001

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6

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47

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Jonathan N Pruneda

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2012-08-09T00:00:00Z

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230653284

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22885007

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3462262

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