Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit - Wikidata - awgldk - TriplyDB

Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit

Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit

http://www.wikidata.org/entity/Q36291492

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Mammalian nicotinic acetylcholine receptors: from structure to function Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration Mechanistic insights into nicotine withdrawal.Negative affective states and cognitive impairments in nicotine dependence Nicotine withdrawal.Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway Dissociation of tolerance and nicotine withdrawal-associated deficits in contextual fear.Mouse models for studying genetic influences on factors determining smoking cessation success in humans.Strain-dependent effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning.The duration of nicotine withdrawal-associated deficits in contextual fear conditioning parallels changes in hippocampal high affinity nicotinic acetylcholine receptor upregulation.Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits.Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice.Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice Noribogaine reduces nicotine self-administration in rats.A Drosophila model for developmental nicotine exposure.In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening.Reward, addiction, withdrawal to nicotine.Targeted deletion of the mouse α2 nicotinic acetylcholine receptor subunit gene (Chrna2) potentiates nicotine-modulated behaviors.Activation of GABAergic neurons in the interpeduncular nucleus triggers physical nicotine withdrawal symptoms.Scientific overview: 2013 BBC plenary symposium on tobacco addiction.The effects of aging vs. α7 nAChR subunit deficiency on the mouse brain transcriptome: aging beats the deficiency.Role of α7- and β4-containing nicotinic acetylcholine receptors in the affective and somatic aspects of nicotine withdrawal: studies in knockout mice.Assessment of affective and somatic signs of ethanol withdrawal in C57BL/6J mice using a short-term ethanol treatment Nicotinic receptor contributions to smoking: insights from human studies and animal models Modulation of aggressive behavior in mice by nicotinic receptor subtypes.Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies.Mesolimbic dopamine and habenulo-interpeduncular pathways in nicotine withdrawal.Unraveling the neurobiology of nicotine dependence using genetically engineered mice Influence of neuronal nicotinic receptors over nicotine addiction and withdrawal.Cellular events in nicotine addiction.Nicotinic receptors containing the alpha7 subunit: a model for rational drug design.Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions.From smoking to lung cancer: the CHRNA5/A3/B4 connection.Insights into nicotinic receptor signaling in nicotine addiction: Implications for prevention and treatment.In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.Repeated mild traumatic brain injury produces neuroinflammation, anxiety-like behaviour and impaired spatial memory in mice.Wheel running during chronic nicotine exposure is protective against mecamylamine-precipitated withdrawal and up-regulates hippocampal α7 nACh receptors in mice.

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P2860

Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit

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J.NEUROPHARM.2007.08.017

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P2860

Alpha7 nicotinic receptor subunits are not necessary for hippocampal-dependent learning or sensorimotor gating: a behavioral characterization of Acra7-deficient mice.

Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies

Nicotinic acetylcholine receptors: from structure to brain function

Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes

Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors

Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation

Nesbitt's Paradox resolved? Stress and arousal modulation during cigarette smoking

Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit

Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse

Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei

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