Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
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Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.Role of microglia in a mouse model of paediatric traumatic brain injuryCombination of ginsenoside Rb1 and Rd protects the retina against bright light-induced degenerationProgesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.Celastrol protects mouse retinas from bright light-induced degeneration through inhibition of oxidative stress and inflammation.Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina.Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor After Sodium Iodate InjuryAugmented expression of TSPO after intracerebral hemorrhage: a role in inflammation?Comprehensive analysis of mouse retinal mononuclear phagocytes.Minocycline has anti-inflammatory effects and reduces cytotoxicity in an ex vivo spinal cord slice culture model of West Nile virus infection.Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.Tamoxifen Provides Structural and Functional Rescue in Murine Models of Photoreceptor Degeneration.Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration.Minocycline modulates microglia polarization in ischemia-reperfusion model of retinal degeneration and induces neuroprotection.Microglial-induced Müller cell gliosis is attenuated by progesterone in a mouse model of retinitis pigmentosa.Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease?Oligodendrocyte death, neuroinflammation, and the effects of minocycline in a rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION).Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa.PERK and XBP1 differentially regulate CXCL10 and CCL2 production.Microglia Activation and Immunomodulatory Therapies for Retinal Degenerations.Modulation of three key innate immune pathways for the most common retinal degenerative diseasesImmunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage
P2860
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P2860
Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
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2015年学术文章
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name
Minocycline counter-regulates ...... and protects from degeneration
@ast
Minocycline counter-regulates ...... and protects from degeneration
@en
type
label
Minocycline counter-regulates ...... and protects from degeneration
@ast
Minocycline counter-regulates ...... and protects from degeneration
@en
prefLabel
Minocycline counter-regulates ...... and protects from degeneration
@ast
Minocycline counter-regulates ...... and protects from degeneration
@en
P2093
P2860
P921
P1476
Minocycline counter-regulates ...... and protects from degeneration
@en
P2093
Albert Caramoy
Christoph Moehle
Markus Sobotka
Rebecca Scholz
Thomas Langmann
Thomas Stempfl
P2860
P2888
P356
10.1186/S12974-015-0431-4
P577
2015-11-17T00:00:00Z
P5875
P6179
1051651351