Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage.
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Single-Atom Imino Substitutions at A9 and A10 Reveal Distinct Effects on the Fold and Function of the Hairpin Ribozyme Catalytic CoreCatalytic importance of a protonated adenosine in the hairpin ribozyme active siteMolecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme.Cobalt(III)hexaammine-dependent photocrosslinks in the hairpin ribozyme.The dawn of the RNA World: toward functional complexity through ligation of random RNA oligomers.Challenges and Perspectives in Nucleic Acid Enzyme Engineering.Design of hairpin ribozyme variants with improved activity for poorly processed substrates.
P2860
Q27656728-F9898985-C12F-43AE-B355-67EBA563FCD9Q35235096-19AD3A52-20F8-4127-9F01-E5F0ADBCCCDEQ37142097-0964AE2B-2346-4DAE-AD51-567FB887C2B4Q37498611-EABFA138-428D-4A16-B6FF-4A49F206C433Q42134880-73B0A3FC-D4C4-4D2D-897C-DC6F4B6682D9Q47835489-2E6314E6-F580-41F0-84C3-71135574E351Q53278500-A828DBD4-33E5-4BA1-9D28-65E004F7D3F9
P2860
Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage.
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2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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name
Mutational inhibition of ligat ...... selectively promote cleavage.
@ast
Mutational inhibition of ligat ...... selectively promote cleavage.
@en
type
label
Mutational inhibition of ligat ...... selectively promote cleavage.
@ast
Mutational inhibition of ligat ...... selectively promote cleavage.
@en
prefLabel
Mutational inhibition of ligat ...... selectively promote cleavage.
@ast
Mutational inhibition of ligat ...... selectively promote cleavage.
@en
P2093
P2860
P356
P1433
P1476
Mutational inhibition of ligat ...... selectively promote cleavage.
@en
P2093
John M Burke
Joyce E Heckman
Snigdha Gaur
P2860
P356
10.1261/RNA.716108
P407
P577
2007-11-12T00:00:00Z