The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling
about
Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartmentPPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis.MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-RasThe Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.R-Ras protein inhibits autophosphorylation of vascular endothelial growth factor receptor 2 in endothelial cells and suppresses receptor activation in tumor vasculature.Resistance of R-Ras knockout mice to skin tumour inductionRegulation of β-adrenergic receptor trafficking and lung microvascular endothelial cell permeability by Rab5 GTPase.Integrin endosomal signalling suppresses anoikis.The availability of the embryonic TGF-β protein Nodal is dynamically regulated during glioblastoma multiforme tumorigenesis.Lack of R-Ras Leads to Increased Vascular Permeability in Ischemic Retinopathy.Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis.Vinculin and Rab5 complex is required [correction of requited]for uptake of Staphylococcus aureus and interleukin-6 expressionSpatially restricted G protein-coupled receptor activity via divergent endocytic compartments.Integrin traffic - the update.Low-intensity pulsed ultrasound promotes cell motility through vinculin-controlled Rac1 GTPase activity.IQGAP1 is a key node within the small GTPase networkThe Role of Embryonic Stem Cell-expressed RAS (ERAS) in the Maintenance of Quiescent Hepatic Stellate Cells.A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.Rab'ing tumor cell migration and invasion: focal adhesion disassembly driven by Rab5.Role of Rab5 in the formation of macrophage-derived foam cell.R-Ras deficiency does not affect papain-induced IgE production in mice.A tale of three GTPases and a RIN in endothelial cell adhesion.Whole-Genome Sequencing of African Dogs Provides Insights into Adaptations against Tropical Parasites.TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration.Regulation of early endosomes across eukaryotes: Evolution and functional homology of Vps9 proteins.ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential.RIT1 controls actin dynamics via complex formation with RAC1/CDC42 and PAK1.Cancer- and behavior-related genes are targeted by selection in the Tasmanian devil (Sarcophilus harrisii)
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The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The R-Ras/RIN2/Rab5 complex co ...... endocytosis and Rac signaling
@ast
The R-Ras/RIN2/Rab5 complex co ...... endocytosis and Rac signaling
@en
type
label
The R-Ras/RIN2/Rab5 complex co ...... endocytosis and Rac signaling
@ast
The R-Ras/RIN2/Rab5 complex co ...... endocytosis and Rac signaling
@en
prefLabel
The R-Ras/RIN2/Rab5 complex co ...... endocytosis and Rac signaling
@ast
The R-Ras/RIN2/Rab5 complex co ...... endocytosis and Rac signaling
@en
P2093
P2860
P50
P921
P356
P1433
P1476
The R-Ras/RIN2/Rab5 complex co ...... endocytosis and Rac signaling
@en
P2093
Chiara Camillo
Chiara Sandri
Francesca Caccavari
Martina Santambrogio
Stefan Veltel
P2860
P2888
P304
P356
10.1038/CR.2012.110
P577
2012-07-24T00:00:00Z