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Inhibition of topoisomerase I prevents chromosome breakage at common fragile sitesAdaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancerRoles of Werner syndrome protein in protection of genome integrityComparative genomics and molecular dynamics of DNA repeats in eukaryotesExpression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinomaThe PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivoTumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogasterWWOX, the chromosomal fragile site FRA16D spanning gene: its role in metabolism and contribution to cancerAn HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesisGene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolutionRECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenanceATR: an essential regulator of genome integrityDeletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humansDDB1 maintains genome integrity through regulation of Cdt1ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery.The role of the Fanconi anemia network in the response to DNA replication stress.CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity.Role for hACF1 in the G2/M damage checkpoint.Copy number variation of the SELENBP1 gene in schizophreniaThe RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stallingMammalian NUMT insertion is non-randomMitotic misbehavior of a Drosophila melanogaster satellite in ring chromosomes: insights into intragenomic conflict among heterochromatic sequences.Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species.Genetic or epigenetic silencing of low density lipoprotein receptor-related protein 1B expression in oral squamous cell carcinoma.Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation.An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiaeDeletion at fragile sites is a common and early event in Barrett's esophagus.Tandem repeats and G-rich sequences are enriched at human CNV breakpointsIncreased common fragile site expression, cell proliferation defects, and apoptosis following conditional inactivation of mouse Hus1 in primary cultured cells.Chromosomal radiosensitivity of human immunodeficiency virus positive/negative cervical cancer patients in South Africa.DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients.Human cytomegalovirus (HCMV) and hearing impairment: infection of fibroblast cells with HCMV induces chromosome breaks at 1q23.3, between loci DFNA7 and DFNA49 -- both involved in dominantly inherited, sensorineural, hearing impairment.Molecular cytogenetic characterization of two independent karyotypic anomalies in a patient with severe mental retardation and juvenile idiopathic arthritisMechanisms leading to nonrandom, nonhomologous chromosomal translocations in leukemiaReplication fork stalling at natural impediments.DNA-protein crosslinks processed by nucleotide excision repair and homologous recombination with base and strand preference in E. coli model system.Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system.Features of trinucleotide repeat instability in vivo.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Mechanisms of common fragile site instability.
@ast
Mechanisms of common fragile site instability.
@en
type
label
Mechanisms of common fragile site instability.
@ast
Mechanisms of common fragile site instability.
@en
prefLabel
Mechanisms of common fragile site instability.
@ast
Mechanisms of common fragile site instability.
@en
P2093
P356
P1476
Mechanisms of common fragile site instability
@en
P2093
Martin F Arlt
Sandra G Durkin
Thomas W Glover
P304
P356
10.1093/HMG/DDI265
P478
14 Spec No. 2
P577
2005-10-01T00:00:00Z