Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.

Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.

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http://www.wikidata.org/entity/Q36294686
The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17Emerging Insights into the Roles of Membrane Tethers from Analysis of Whole Organisms: The Tip of an Iceberg?Homozygous mutation of VPS16 gene is responsible for an autosomal recessive adolescent-onset primary dystoniaSpecific distribution of the autophagic protein GABARAPL1/GEC1 in the developing and adult mouse brain and identification of neuronal populations expressing GABARAPL1/GEC1.Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation.Autophagy: regulation and role in developmentCaenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1.Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila.Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.Cellular Signature of SIL1 Depletion: Disease Pathogenesis due to Alterations in Protein Composition Beyond the ER Machinery.hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins.
P2860

Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.

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http://www.wikidata.org/entity/Q36294686
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2012 nî lūn-bûn
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name
Ablation of vacuole protein so ...... ansport pathways to lysosomes.
@ast
Ablation of vacuole protein so ...... ansport pathways to lysosomes.
@en
type
label
Ablation of vacuole protein so ...... ansport pathways to lysosomes.
@ast
Ablation of vacuole protein so ...... ansport pathways to lysosomes.
@en
prefLabel
Ablation of vacuole protein so ...... ansport pathways to lysosomes.
@ast
Ablation of vacuole protein so ...... ansport pathways to lysosomes.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
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P1433
P1476
Ablation of vacuole protein so ...... ransport pathways to lysosomes
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932