Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley ratsThe plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease.Antihypertensive effect of auraptene, a monoterpene coumarin from the genus Citrus, upon chronic administration.Auraptene, a Major Compound of Supercritical Fluid Extract of Phalsak (Citrus Hassaku Hort ex Tanaka), Induces Apoptosis through the Suppression of mTOR Pathways in Human Gastric Cancer SNU-1 Cells.Auraptene and its effects on the re-emergence of colon cancer stem cells.Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7.Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation.Auraptene: a natural biologically active compound with multiple targets.Novel prodrugs for the treatment of colonic diseases based on 5-aminosalicylic acid, 4'-geranyloxyferulic acid, and auraptene: biological activities and analytical assays.Auraptene Attenuates Malignant Properties of Esophageal Stem-Like Cancer Cells.Stimulation of phosphorylation of ERK and CREB by phellopterin and auraptene isolated from Citrusjunos.Auraptene and Its Role in Chronic Diseases.Anti-inflammatory and wound healing potential of citrus auraptene.Anti-inflammatory effect of auraptene extracted from trifoliate orange (Poncirus trifoliate) on LPS-stimulated RAW 264.7 cells.Auraptene suppresses inflammatory responses in activated RAW264 macrophages by inhibiting p38 mitogen-activated protein kinase activation.Neurotrophic effect of citrus auraptene: neuritogenic activity in PC12 cells.Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors.Suppression of CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation-activated ERK1/2 in NCI-N87 gastric carcinoma cells.Neuroprotective and memory enhancing effects of auraptene in a rat model of vascular dementia: Experimental study and histopathological evaluation.Auraptene, a citrus fruit compound, regulates gene expression as a PPARalpha agonist in HepG2 hepatocytes.Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism.Auraptene in the Peels of Citrus kawachiensis (Kawachi Bankan) Ameliorates Lipopolysaccharide-Induced Inflammation in the Mouse Brain.Suppressing effects of dietary supplementation of the organoselenium 1,4-phenylenebis(methylene)selenocyanate and the Citrus antioxidant auraptene on lung metastasis of melanoma cells in mice.In vitro absorption and metabolism of a citrus chemopreventive agent, auraptene, and its modifying effects on xenobiotic enzyme activities in mouse livers.Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes.Auraptene and Other Prenyloxyphenylpropanoids Suppress Microglial Activation and Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson's DiseaseChemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by citrus auraptene in rats.Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4'-geranyloxyferulic acid.Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells.Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes.Auraptene consolidates memory, reverses scopolamine-disrupted memory in passive avoidance task, and ameliorates retention deficits in mice.Citrus auraptene reduces Helicobacter pylori colonization of glandular stomach lesions in Mongolian gerbils.Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp.Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis.Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress.Anti-inflammatory and neuroprotective effects of auraptene, a citrus coumarin, following cerebral global ischemia in mice.Auraptene Induces Apoptosis via Myeloid Cell Leukemia 1-Mediated Activation of Caspases in PC3 and DU145 Prostate Cancer Cells.Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats.Metabolism and absorption of auraptene (7-geranyloxylcoumarin) in male SD rats: comparison with 7-ethoxycoumarin.Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice.
P921
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P921
description
chemesch Verbindung
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chemical compound
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chemical compound
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chemical compound
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chemická sloučenina
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chemická zlúčenina
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chemiese verbinding
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chemische Verbindung
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chemische Verbindung
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chemische verbinding
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Aurapten
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Aurapten
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Aurapten
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Auraptene
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Auraptene
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اوراپتن
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Aurapten
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auraptene
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auraptene
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اوراپتن
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اوراپتن
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C19H22O3
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C19H22O3, オーラプテン
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P6366
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CC(=CCC/C(=C/COC1=CC2=C(C=C1)C=CC(=O)O2)/C)C
P2067
P2085
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P233
CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C
P234
1S/C19H22O3/c1-14(2)5-4-6-15(3 ...... -11,13H,4,6,12H2,1-3H3/b15-11+
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splash10-08fr-1900000000-b149439e3218a537d0ac
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CHEMBL307341
P6366
2781457552
P646
/m/02q8dr4
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F79I1ZEL2E