A suite of modular fluorescence assays interrogate the human immunodeficiency virus glycoprotein-41 coiled coil and assist in determining binding mechanism of low molecular weight fusion inhibitors.
about
Identification of fragments targeting an alternative pocket on HIV-1 gp41 by NMR screening and similarity searching.Design and characterization of swapped-domain constructs of HIV-1 glycoprotein-41 as receptors for drug discovery.Enhanced potency of bivalent small molecule gp41 inhibitors.NMR-assisted computational studies of peptidomimetic inhibitors bound in the hydrophobic pocket of HIV-1 glycoprotein 41.Small molecule inhibitors of HIVgp41 N-heptad repeat trimer formation.Swapped-domain constructs of the glycoprotein-41 ectodomain are potent inhibitors of HIV infectionEvaluation of ligand-based NMR screening methods to characterize small molecule binding to HIV-1 glycoprotein-41.Structure-activity relationship studies of indole-based compounds as small molecule HIV-1 fusion inhibitors targeting glycoprotein 41.
P2860
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P2860
A suite of modular fluorescence assays interrogate the human immunodeficiency virus glycoprotein-41 coiled coil and assist in determining binding mechanism of low molecular weight fusion inhibitors.
description
2012 nî lūn-bûn
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name
A suite of modular fluorescenc ...... ular weight fusion inhibitors.
@ast
A suite of modular fluorescenc ...... ular weight fusion inhibitors.
@en
type
label
A suite of modular fluorescenc ...... ular weight fusion inhibitors.
@ast
A suite of modular fluorescenc ...... ular weight fusion inhibitors.
@en
prefLabel
A suite of modular fluorescenc ...... ular weight fusion inhibitors.
@ast
A suite of modular fluorescenc ...... ular weight fusion inhibitors.
@en
P2860
P356
P1476
A suite of modular fluorescenc ...... ular weight fusion inhibitors.
@en
P2093
Miriam Gochin
P2860
P304
P356
10.1089/ADT.2012.464
P577
2012-08-16T00:00:00Z