A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
about
Identification of JL1037 as a novel, specific, reversible lysine-specific demethylase 1 inhibitor that induce apoptosis and autophagy of AML cellsOncogenic K-ras confers SAHA resistance by up-regulating HDAC6 and c-myc expression.Histone deacetylases function as a novel potential therapeutic target for cancer.The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.
P2860
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
@zh-hant
name
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
@ast
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
@en
type
label
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
@ast
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
@en
prefLabel
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
@ast
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
@en
P2093
P2860
P356
P1433
P1476
A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.
@en
P2093
Dianwu Guo
Haiyan Xing
Jianxiang Wang
Shaowei Qiu
Shouyun Li
P2860
P304
20121-20131
P356
10.18632/ONCOTARGET.4041
P407
P577
2015-05-08T00:00:00Z