Delivery of exogenous tetrahydrobiopterin (BH4) to cells of target organs: role of salvage pathway and uptake of its precursor in effective elevation of tissue BH4.
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Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytesQueuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidationTetrahydrobiopterin Supplementation: Elevation of Tissue Biopterin Levels Accompanied by a Relative Increase in Dihydrobiopterin in the Blood and the Role of Probenecid-Sensitive Uptake in Scavenging Dihydrobiopterin in the Liver and Kidney of RatsTetrahydrobiopterin in the prevention of hypertonia in hypoxic fetal brain.Increasing tetrahydrobiopterin in cardiomyocytes adversely affects cardiac redox state and mitochondrial function independently of changes in NO production.Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.Tetrahydrobiopterin Inhibits PDGF-stimulated Migration and Proliferation in Rat Aortic Smooth Muscle Cells via the Nitric Oxide Synthase-independent Pathway.Sepiapterin reverses the changes in gastric nNOS dimerization and function in diabetic gastroparesisSepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase.Phage-display-guided nanocarrier targeting to atheroprone vasculature.Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4).GCH1, BH4 and painNovel strategies to ameliorate radiation injury: a possible role for tetrahydrobiopterinBiochemical characterization of the tetrahydrobiopterin synthesis pathway in the oleaginous fungus Mortierella alpina.Nitric oxide homeostasis as a target for drug additives to cardioplegiaVascular protection by tetrahydrobiopterin: progress and therapeutic prospectsTetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.Psychiatric manifestations in cerebrotendinous xanthomatosis.Modulating endothelial nitric oxide synthase: a new cardiovascular therapeutic strategy.Production and Peripheral Roles of 5-HTP, a Precursor of Serotonin.Combining Human and Rodent Genetics to Identify New Analgesics.Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cellsSapropterin Dihydrochloride Mixed With Common Foods and Beverages.Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess.Components of the folate metabolic pathway and ADHD core traits: an exploration in eastern Indian probands.
P2860
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P2860
Delivery of exogenous tetrahydrobiopterin (BH4) to cells of target organs: role of salvage pathway and uptake of its precursor in effective elevation of tissue BH4.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Delivery of exogenous tetrahyd ...... ctive elevation of tissue BH4.
@ast
Delivery of exogenous tetrahyd ...... ctive elevation of tissue BH4.
@en
type
label
Delivery of exogenous tetrahyd ...... ctive elevation of tissue BH4.
@ast
Delivery of exogenous tetrahyd ...... ctive elevation of tissue BH4.
@en
prefLabel
Delivery of exogenous tetrahyd ...... ctive elevation of tissue BH4.
@ast
Delivery of exogenous tetrahyd ...... ctive elevation of tissue BH4.
@en
P2093
P1476
Delivery of exogenous tetrahyd ...... ctive elevation of tissue BH4.
@en
P2093
Hiroyuki Hasegawa
Keiko Sawabe
Nobuo Nakanishi
Osuke K Wakasugi
P356
10.1016/J.YMGME.2005.09.002
P478
86 Suppl 1
P577
2005-10-25T00:00:00Z