Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis.
about
MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinaseCharacterization of the promoter for the human 85 kDa cytosolic phospholipase A2 geneInterferon-alpha-induced phosphorylation and activation of cytosolic phospholipase A2 is required for the formation of interferon-stimulated gene factor threeIdentification of a 27 bp 5'-flanking region element responsible for the low level constitutive expression of the human cytosolic phospholipase A2 geneIdentification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays.Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activityP11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2Induction of Galphas contributes to the paradoxical stimulation of cytosolic phospholipase A2alpha expression by cortisol in human amnion fibroblasts.Corticosterone suppresses IL-1β-induced mPGE2 expression through regulation of the 11β-HSD1 bioactivity of synovial fibroblasts in vitroIncreased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients.Interleukin 1 alpha causes rapid activation of cytosolic phospholipase A2 by phosphorylation in rat mesangial cells.Interleukin 4 suppresses c-kit ligand-induced expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase 2 and their roles in separate pathways of eicosanoid synthesis in mouse bone marrow-derived mast cells.Imaging upregulated brain arachidonic acid metabolism in HIV-1 transgenic ratsCoordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging.Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites.TNF ligands and receptors--a matter of life and death.Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells.Current and emerging strategies for the treatment and management of systemic lupus erythematosus based on molecular signatures of acute and chronic inflammationCo-compartmentalization of MAP kinases and cytosolic phospholipase A2 at cytoplasmic arachidonate-rich lipid bodies.The adenovirus E3 10.4K and 14.5K proteins, which function to prevent cytolysis by tumor necrosis factor and to down-regulate the epidermal growth factor receptor, are localized in the plasma membraneThe adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid.Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes.Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway.Neuroinflammation and synaptic lossPlatelet-activating factor-mediated NF-kappaB dependency of a late anaphylactic reactionCytosolic phospholipase A2-alpha: a potential therapeutic target for prostate cancerA novel signaling mechanism between gas and blood compartments of the lungPhospholipase A2 in meconium-induced lung injury.New developments on the TNFα-mediated signalling pathways.Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia.Effects of the inhibition of cytosolic phospholipase A(2)α in non-small cell lung cancer cells.Two distinct pathways for cyclooxygenase-2 protein degradation.Cytokine regulation of mast cell protease phenotype and arachidonic acid metabolism.A study of the anti-pyretic effect of quinine, an alkaloid effective against cerebral malaria, on fever induced by bacterial endotoxin and yeast in rats.Tumor necrosis factor receptor-mediated signaling pathways.Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.Molecular mechanisms for lipopolysaccharide-induced biphasic activation of nuclear factor-kappa B (NF-kappa B).85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells.Upregulation of lipocortin 1 inhibits tumour necrosis factor-induced apoptosis in human leukaemic cells: a possible mechanism of resistance to immune surveillance.
P2860
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P2860
Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Cytoplasmic phospholipase A2 a ...... blocks the induced synthesis.
@ast
Cytoplasmic phospholipase A2 a ...... blocks the induced synthesis.
@en
type
label
Cytoplasmic phospholipase A2 a ...... blocks the induced synthesis.
@ast
Cytoplasmic phospholipase A2 a ...... blocks the induced synthesis.
@en
prefLabel
Cytoplasmic phospholipase A2 a ...... blocks the induced synthesis.
@ast
Cytoplasmic phospholipase A2 a ...... blocks the induced synthesis.
@en
P2093
P2860
P356
P1476
Cytoplasmic phospholipase A2 a ...... blocks the induced synthesis.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.10.4475
P407
P577
1993-05-01T00:00:00Z