Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
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Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeuticsPre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma ModelsDetection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma.Pediatric high-grade glioma: biologically and clinically in need of new thinkingTargeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas.Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma.A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells.Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.Recent advances and future of immunotherapy for glioblastoma.Genomic Insights into Diffuse Intrinsic Pontine Glioma.Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal diseaseEMT- and MET-related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities.Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.Advances in the molecular genetics of gliomas - implications for classification and therapy.Low-grade epilepsy-associated neuroepithelial tumours - the 2016 WHO classification.Oncogenic Mechanisms of Histone H3 Mutations.The new WHO 2016 classification of brain tumors-what neurosurgeons need to know.Co-occurrence of histone H3 K27M and BRAF V600E mutations in paediatric midline grade I ganglioglioma.Modeling and Targeting MYC Genes in Childhood Brain Tumors.Pediatric high-grade glioma: current molecular landscape and therapeutic approaches.Characterization of gliomas: from morphology to molecules.External validation of the diffuse intrinsic pontine glioma survival prediction model: a collaborative report from the International DIPG Registry and the SIOPE DIPG Registry.New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis.Imaging Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3 K27M Mutation.The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner.Positron emission tomography imaging in diffuse intrinsic pontine glioma.The pharmacological role of histone demethylase JMJD3 inhibitor GSK-J4 on glioma cells.Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition.Histone H3 genotyping refines clinico-radiological diagnostic and prognostic criteria in DIPG.Intratumoral heterogeneity and clonal evolution in blood malignancies and solid tumors.Commentary on "Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes".A clinical perspective on the 2016 WHO brain tumor classification and routine molecular diagnostics.Immunotherapy for Pediatric Brain Tumors.Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression.Development of Chemotherapy with Cell-Cycle Inhibitors for Adult and Pediatric Cancer Therapy.Significance of H3K27M mutation with specific histomorphological features and associated molecular alterations in pediatric high-grade glial tumors.Diffuse intrinsic pontine gliomas-current management and new biologic insights. Is there a glimmer of hope?Diagnostic implications of TERT promoter mutation status in diffuse gliomas in a routine clinical setting.
P2860
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P2860
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Histone H3F3A and HIST1H3B K27 ...... erent prognosis and phenotypes
@ast
Histone H3F3A and HIST1H3B K27 ...... erent prognosis and phenotypes
@en
type
label
Histone H3F3A and HIST1H3B K27 ...... erent prognosis and phenotypes
@ast
Histone H3F3A and HIST1H3B K27 ...... erent prognosis and phenotypes
@en
prefLabel
Histone H3F3A and HIST1H3B K27 ...... erent prognosis and phenotypes
@ast
Histone H3F3A and HIST1H3B K27 ...... erent prognosis and phenotypes
@en
P2093
P2860
P50
P1476
Histone H3F3A and HIST1H3B K27 ...... erent prognosis and phenotypes
@en
P2093
Alan Mackay
Cathy Philippe
Christian Sainte-Rose
Kathryn R Taylor
Ludivine Le Dret
Ludovic Lacroix
Marie-Anne Debily
Mélanie Pagès
Nathalène Truffaux
Patrick Saulnier
P2860
P2888
P304
P356
10.1007/S00401-015-1478-0
P577
2015-09-23T00:00:00Z