Alpha1,3-galactosyltransferase knockout pigs are available for xenotransplantation: are glycosyltransferases still relevant?
about
Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens.The xenoantibody response and immunoglobulin gene expression profile of cynomolgus monkeys transplanted with hDAF-transgenic porcine hearts.Identification of an anti-idiotypic antibody that defines a B-cell subset(s) producing xenoantibodies in primates.Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograftABO blood group and related antigens, natural antibodies and transplantation.Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammalsXenotransplantation literature update November-December 2005.Lack of iGb3 and Isoglobo-Series Glycosphingolipids in Pig Organs Used for Xenotransplantation: Implications for Natural Killer T-Cell Biology.Gal knockout and beyond.CD1d presentation of glycolipids.Structural biology of carbohydrate xenoantigens.Carbohydrate residues downstream of the terminal Galalpha(1,3)Gal epitope modulate the specificity of xenoreactive antibodies.Xenotransfusions, past and present.Silencing the porcine iGb3s gene does not affect Galα3Gal levels or measures of anticipated pig-to-human and pig-to-primate acute rejection.Optimized decellularization protocol including α-Gal epitope reduction for fabrication of an acellular porcine annulus fibrosus scaffold.Distribution of the alphaGal- and the non-alphaGal T-antigens in the pig kidney: potential targets for rejection in pig-to-man xenotransplantation.Encouraging experience using multi-transgenic xenografts in a pig-to-baboon cardiac xenotransplantation model.Tick galactosyltransferases are involved in α-Gal synthesis and play a role during Anaplasma phagocytophilum infection and Ixodes scapularis tick vector developmentGal epitope expression and immunological properties in iGb3S deficient mice
P2860
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P2860
Alpha1,3-galactosyltransferase knockout pigs are available for xenotransplantation: are glycosyltransferases still relevant?
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Alpha1,3-galactosyltransferase ...... yltransferases still relevant?
@ast
Alpha1,3-galactosyltransferase ...... yltransferases still relevant?
@en
type
label
Alpha1,3-galactosyltransferase ...... yltransferases still relevant?
@ast
Alpha1,3-galactosyltransferase ...... yltransferases still relevant?
@en
prefLabel
Alpha1,3-galactosyltransferase ...... yltransferases still relevant?
@ast
Alpha1,3-galactosyltransferase ...... yltransferases still relevant?
@en
P2860
P1476
Alpha1,3-galactosyltransferase ...... yltransferases still relevant?
@en
P2093
Dale Christiansen
Mauro S Sandrin
P2860
P304
P356
10.1111/J.1440-1711.2005.01398.X
P577
2005-12-01T00:00:00Z