Inflammation-activated protein kinases as targets for drug development
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TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathwayDifferences in Inflammatory Response Induced by Two Representatives of Clades of the Pandemic ST258 Klebsiella pneumoniae Clonal Lineage Producing KPC-Type Carbapenemases.c-Jun N-terminal kinase activation contributes to reduced connexin43 and development of atrial arrhythmias.Attenuation of Carcinogenesis and the Mechanism Underlying by the Influence of Indole-3-carbinol and Its Metabolite 3,3'-Diindolylmethane: A Therapeutic MarvelExpression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes.Surgical intervention for symptomatic benign prostatic hyperplasia is correlated with expression of the AP-1 transcription factor networkTargeting L1 cell adhesion molecule expression using liposome-encapsulated siRNA suppresses prostate cancer bone metastasis and growth.Arvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinaseNF-kappaB, but not p38 MAP kinase, is required for TNF-alpha-induced expression of cell adhesion molecules in endothelial cells.Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to LipopolysaccharideRhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathwaysActivator protein 1 (Fos/Jun) functions in inflammatory bone and skin diseaseHuman biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling.Suppression of TLR signaling by targeting TIR domain-containing proteinsMechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages.Gene signatures related to HAI response following influenza A/H1N1 vaccine in older individuals.Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites.Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury.Vascular plasticity in cerebrovascular disorders.Cyclic AMP: a selective modulator of NF-κB action.Moringa fruit inhibits LPS-induced NO/iNOS expression through suppressing the NF-κ B activation in RAW264.7 cells.Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s Interaction.Innovative computer-aided methods for the discovery of new kinase ligands.Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TAK-IKK and TAK-JNK/p38MAPK pathways in RAW264.7 macrophagesActivation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism.Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway.Tumor necrosis factor receptor-associated factor-6 and ribosomal S6 kinase intracellular pathways link the angiotensin II AT1 receptor to the phosphorylation and activation of the IkappaB kinase complex in vascular smooth muscle cells.MG132 proteasome inhibitor modulates proinflammatory cytokines production and expression of their receptors in U937 cells: involvement of nuclear factor-kappaB and activator protein-1.The host inflammatory response promotes liver metastasis by increasing tumor cell arrest and extravasation.The influence of Sam-Chil-Geun (Panax notoginseng) on the serum lipid levels and inflammations of rats with hyperlipidemia induced by poloxamer-407.Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation.Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw.Inflammation in Diabetic Encephalopathy is Prevented by C-Peptide.Role of MAP kinases and PI3K-Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients.Genistein induces oestrogen receptor-α gene expression in osteoblasts through the activation of mitogen-activated protein kinases/NF-κB/activator protein-1 and promotes cell mineralisation.The effect of tiotropium bromide on health-related quality of life in chronic obstructive pulmonary disease.Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways.Inflammatory Activation of Microglia and Astrocytes in Manganese Neurotoxicity.Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis.Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis via induction of Nrf2 and suppression of NF-κB and MAPK signalling.
P2860
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P2860
Inflammation-activated protein kinases as targets for drug development
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Inflammation-activated protein kinases as targets for drug development
@ast
Inflammation-activated protein kinases as targets for drug development
@en
type
label
Inflammation-activated protein kinases as targets for drug development
@ast
Inflammation-activated protein kinases as targets for drug development
@en
prefLabel
Inflammation-activated protein kinases as targets for drug development
@ast
Inflammation-activated protein kinases as targets for drug development
@en
P2860
P1476
Inflammation-activated protein kinases as targets for drug development
@en
P2860
P304
386-90; discussion 394-5
P356
10.1513/PATS.200504-034SR
P577
2005-01-01T00:00:00Z