Drosophila as a model for human neurodegenerative disease.
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Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicityExtracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein AlfyAnimal models of polyglutamine diseases and therapeutic approachesBiology of ageing and role of dietary antioxidantsAxonal transport disruption in peripheral nerve disease: From Jack's discoveries as a resident to recent contributionsA drosophila model for EGFR-Ras and PI3K-dependent human gliomadAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1Genome-wide screen for modifiers of ataxin-3 neurodegeneration in DrosophilaUltrastructural modifications in the mitochondria of hypoxia-adapted Drosophila melanogasterHigh-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease modelTriplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy3D Holographic Observatory for Long-term Monitoring of Complex Behaviors in Drosophila.Role of Drosophila Amyloid Precursor Protein in Memory FormationThe interplay between obesity and cancer: a fly viewThe aminoacyl-tRNA synthetases of Drosophila melanogasterDrosophila as an In Vivo Model for Human Neurodegenerative DiseaseSelective degeneration of dopaminergic neurons by MPP(+) and its rescue by D2 autoreceptors in Drosophila primary cultureEnhanced neuronal glucose transporter expression reveals metabolic choice in a HD Drosophila modelCurcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic DrosophilaSystematic Aβ Analysis in Drosophila Reveals High Toxicity for the 1-42, 3-42 and 11-42 Peptides, and Emphasizes N- and C-Terminal ResiduesDominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy.Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.Functional conservation of human Spastin in a Drosophila model of autosomal dominant-hereditary spastic paraplegiaHow to innervate a simple gut: familiar themes and unique aspects in the formation of the insect enteric nervous system.A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity.In vivo analysis of compound activity and mechanism of action using epistasis in Drosophila.Repeat length and RNA expression level are not primary determinants in CUG expansion toxicity in Drosophila modelsGuide to understanding Drosophila models of neurodegenerative diseases.Identification of neural outgrowth genes using genome-wide RNAi.A functional misexpression screen uncovers a role for enabled in progressive neurodegeneration.Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch.Drosophotoxicology: the growing potential for Drosophila in neurotoxicologyDual regulation of dendritic morphogenesis in Drosophila by the COP9 signalosome.A Drosophila model for TDP-43 proteinopathy.Transgenic Drosophila models of Alzheimer's disease and tauopathiesSpectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila.Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD modelCold temperature improves mobility and survival in Drosophila models of autosomal-dominant hereditary spastic paraplegia (AD-HSP).Glia are critical for the neuropathology of complex I deficiency in Drosophila
P2860
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P2860
Drosophila as a model for human neurodegenerative disease.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Drosophila as a model for human neurodegenerative disease.
@ast
Drosophila as a model for human neurodegenerative disease.
@en
type
label
Drosophila as a model for human neurodegenerative disease.
@ast
Drosophila as a model for human neurodegenerative disease.
@en
altLabel
Drosophilaas a Model for Human Neurodegenerative Disease
@en
prefLabel
Drosophila as a model for human neurodegenerative disease.
@ast
Drosophila as a model for human neurodegenerative disease.
@en
P1476
Drosophila as a model for human neurodegenerative disease.
@en
P2093
Julide Bilen
P304
P356
10.1146/ANNUREV.GENET.39.110304.095804
P577
2005-01-01T00:00:00Z