Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.

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http://www.wikidata.org/entity/Q36316513
β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancersGenome-scale modeling of NADPH-driven β-lapachone sensitization in head and neck squamous cell carcinoma.Distinct responses of compartmentalized glutathione redox potentials to pharmacologic quinones targeting NQO1.Suppressive effect of topoisomerase inhibitors on JC polyomavirus propagation in human neuroblastoma cells.Using DNA devices to track anticancer drug activity.Targeting reactive oxygen species in development and progression of pancreatic cancer.Emerging protein kinase inhibitors for treating pancreatic cancer.Lysosome-oriented, dual-stage pH-responsive polymeric micelles for β-Lapachone delivery.Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer.The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.Enhancing Oral Absorption of β-Lapachone: Progress Till Date.Carnosic acid, an inducer of NAD(P)H quinone oxidoreductase 1, enhances the cytotoxicity of β-lapachone in melanoma cell lines.A New Strategy to Control and Eradicate "Undruggable" Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary Biology
P2860

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.

Item
http://www.wikidata.org/entity/Q36316513
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
Tumor-selective use of DNA bas ...... activatable drug, β-lapachone.
@ast
Tumor-selective use of DNA bas ...... activatable drug, β-lapachone.
@en
type
label
Tumor-selective use of DNA bas ...... activatable drug, β-lapachone.
@ast
Tumor-selective use of DNA bas ...... activatable drug, β-lapachone.
@en
prefLabel
Tumor-selective use of DNA bas ...... activatable drug, β-lapachone.
@ast
Tumor-selective use of DNA bas ...... activatable drug, β-lapachone.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Tumor-selective use of DNA bas ...... activatable drug, β-lapachone.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P5875
P698
P932