Variable region identical immunoglobulins differing in isotype express different paratopes.
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Ig Constant Region Effects on Variable Region Structure and FunctionElucidating the immunological function of the Cryptococcus neoformans capsuleGlobal structures of IgG isotypes expressing identical variable regionsA peptide mimic blocks the cross-reaction of anti-DNA antibodies with glomerular antigensIBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CABroadly neutralizing anti-influenza virus antibodies: enhancement of neutralizing potency in polyclonal mixtures and IgA backbones.CHO cell production and sequence improvement in the 13C6FR1 anti-Ebola antibody.IgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis.Physiological IgM class catalytic antibodies selective for transthyretin amyloid.Thermodynamic analysis of the binding of 2F5 (Fab and immunoglobulin G forms) to its gp41 epitope reveals a strong influence of the immunoglobulin Fc region on affinity.Variable Region Identical IgA and IgE to Cryptococcus neoformans Capsular Polysaccharide Manifest Specificity Differences.Anti-DNA antibody mediated catalysis is isotype dependent.Inhibition of allergen-dependent IgE activity by antibodies of the same specificity but different class.Contribution of murine IgG Fc regions to antibody binding to the capsule of Burkholderia pseudomallei.A Monoclonal Antibody to Cryptococcus neoformans Glucuronoxylomannan Manifests Hydrolytic Activity for Both Peptides and Polysaccharides.Antibody-Mediated Catalysis in Infection and Immunity.Isotype switching: Mouse IgG3 constant region drives increased affinity for polysaccharide antigens.Aggregates, crystals, gels, and amyloids: intracellular and extracellular phenotypes at the crossroads of immunoglobulin physicochemical property and cell physiology.The constant region affects antigen binding of antibodies to DNA by altering secondary structureThe interdependence of antibody C and V regions on specificity and affinity: significant implications for the engineering of therapeutic antibodies.CAR-T cell therapy in ovarian cancer: from the bench to the bedside.IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development.
P2860
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P2860
Variable region identical immunoglobulins differing in isotype express different paratopes.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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name
Variable region identical immu ...... e express different paratopes.
@ast
Variable region identical immu ...... e express different paratopes.
@en
type
label
Variable region identical immu ...... e express different paratopes.
@ast
Variable region identical immu ...... e express different paratopes.
@en
prefLabel
Variable region identical immu ...... e express different paratopes.
@ast
Variable region identical immu ...... e express different paratopes.
@en
P2860
P50
P356
P1476
Variable region identical immu ...... e express different paratopes.
@en
P2093
Antonio Nakouzi
Ertan Eryilmaz
P2860
P304
35409-35417
P356
10.1074/JBC.M112.404483
P407
P577
2012-08-28T00:00:00Z