Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes. - Wikidata - awgldk - TriplyDB

Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.

Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.

http://www.wikidata.org/entity/Q36320257

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Therapeutic drug monitoring for triazoles: A needs assessment review and recommendations from a Canadian perspective Gender differences in murine pulmonary responses elicited by cellulose nanocrystals Virtual Experiments Enable Exploring and Challenging Explanatory Mechanisms of Immune-Mediated P450 Down-Regulation Assessment of Disease-Related Therapeutic Protein Drug-Drug Interaction for Etrolizumab in Patients With Moderately to Severely Active Ulcerative Colitis Hepatic gene expression profiling reveals protective responses in Atlantic salmon vaccinated against furunculosis Emergency open cholecystectomy is associated with markedly lower incidence of postoperative nausea and vomiting (PONV) than elective open cholecystectomy: a retrospective cohort study The transcriptional regulation of the human CYP2C genes Disease-Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis.Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications.The correlation between the expression of genes involved in drug metabolism and the blood level of tacrolimus in liver transplant receipts DEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytes Pharmacokinetics of mycophenolic acid in patients with lupus nephritis.Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes.A clinical therapeutic protein drug-drug interaction study: coadministration of denosumab and midazolam in postmenopausal women with osteoporosis.Inflammation is associated with voriconazole trough concentrations.Transcriptional regulation of the human P450 oxidoreductase gene: hormonal regulation and influence of promoter polymorphisms.Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosis Selective role for tumor necrosis factor-α, but not interleukin-1 or Kupffer cells, in down-regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen.Impact of infectious and inflammatory disease on cytochrome P450-mediated drug metabolism and pharmacokinetics Modulation of hepatic cytochrome P450s by Citrobacter rodentium infection in interleukin-6- and interferon-{gamma}-null mice Immunological response as a source to variability in drug metabolism and transport.The role of the immune system in nevirapine-induced subclinical liver injury of a rat model.Impact of visceral leishmaniasis and curative chemotherapy on cytochrome P450 activity in Brazilian patients Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19.Maternal obesity alters feto-placental cytochrome P4501A1 activity.Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.Pharmacokinetic and pharmacodynamic properties of canakinumab, a human anti-interleukin-1β monoclonal antibody Profiling of hepatic clearance pathways of Pittsburgh compound B and human liver cytochrome p450 phenotyping.CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells.Regulation of hepatic cytochrome P450 expression in mice with intestinal or systemic infections of citrobacter rodentium.Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing.Dual mechanisms of CYP3A protein regulation by proinflammatory cytokine stimulation in primary hepatocyte cultures.The effect of ZnO nanoparticles on liver function in rats Hepatic cytochrome P450s, phase II enzymes and nuclear receptors are downregulated in a Th2 environment during Schistosoma mansoni infection.Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.Regulation of human hepatic drug transporter expression by pro-inflammatory cytokines.Selective effects of a therapeutic protein targeting tumor necrosis factor-alpha on cytochrome P450 regulation during infectious colitis: Implications for disease-dependent drug-drug interactions.4β-Hydroxycholesterol Level in Patients With Rheumatoid Arthritis Before vs. After Initiation of bDMARDs and Correlation With Inflammatory State.Interleukin-6 and cytochrome-P450, reason for concern?

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P2860

Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.

http://www.wikidata.org/entity/Q36320257

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2007 nî lūn-bûn

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Gene-specific effects of infla ...... A levels in human hepatocytes.

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Gene-specific effects of infla ...... A levels in human hepatocytes.

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Drug Metabolism and Disposition

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Alison E Aitken

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P2860

Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes

Biochemistry and molecular biology of the human CYP2C subfamily

Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response.

Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR.

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation

Lessons from the CYP3A4 promoter.

Cytochrome P450 regulation and drug biotransformation during inflammation and infection.

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