Intercellular calcium communication regulates platelet aggregation and thrombus growth.
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Thrombus formation in vivo.An EF hand mutation in Stim1 causes premature platelet activation and bleeding in micePlatelet signalingGPVI and integrin alphaIIb beta3 signaling in plateletsThrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury modelLigand density dramatically affects integrin alpha IIb beta 3-mediated platelet signaling and spreading.Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner.Shaping the platelet response to vascular injury.Platelet adhesion under flow.Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entryDesign of a pulsatile flow facility to evaluate thrombogenic potential of implantable cardiac devices.Shear-induced platelet receptor shedding by non-physiological high shear stress with short exposure time: glycoprotein Ibα and glycoprotein VI.A critical role for the transient receptor potential channel type 6 in human platelet activationBruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo.Anti-platelet activity of panaxatriol saponins is mediated by suppression of intracellular calcium mobilization and ERK2/p38 activation.Long-distance calls between cells connected by tunneling nanotubules.Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo.Cytokine-release kinetics of platelet-rich plasma according to various activation protocols.Electrical stimulation drives chondrogenesis of mesenchymal stem cells in the absence of exogenous growth factors.Harnessing the platelet signaling network to produce an optimal hemostatic response.Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.Role of platelet plasma membrane Ca-ATPase in health and disease.Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets.Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner.GPIbalpha-selective activation of platelets induces platelet signaling events comparable to GPVI activation events.Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species.Shear-induced interaction of platelets with von Willebrand factor results in glycoprotein Ibalpha shedding.Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA.Real-time analysis of very late antigen-4 affinity modulation by shear.Importance of temporal flow gradients and integrin alphaIIbbeta3 mechanotransduction for shear activation of platelets.Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway.Cryopreserved platelets demonstrate reduced activation responses and impaired signaling after agonist stimulation.Platelet factor XIII and calpain negatively regulate integrin alphaIIbbeta3 adhesive function and thrombus growth.IPA3 non-specifically enhances phosphorylation of several proteins in human platelets.14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling.Connexins and Pannexins in Vascular Function and DiseaseEffects of Surface Nanotopography and Calcium Chemistry of Titanium Bone Implants on Early Blood Platelet and Macrophage Cell Function
P2860
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P2860
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
@ast
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
@en
type
label
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
@ast
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
@en
prefLabel
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
@ast
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
@en
P2093
P2860
P356
P1476
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
@en
P2093
Ian S Harper
Sacha M Dopheide
Shaun P Jackson
Simon Giuliano
Suhasini Kulkarni
Warwick S Nesbitt
P2860
P304
P356
10.1083/JCB.200207119
P407
P577
2003-03-01T00:00:00Z