HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas.

HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas.

Item
http://www.wikidata.org/entity/Q36323374
Apoptotic pathways as a therapeutic target for colorectal cancer treatmentThe role of p53 in cancer drug resistance and targeted chemotherapyMitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanateNature and importance of follicular lymphoma precursors.p53 abnormalities and potential therapeutic targeting in multiple myeloma.p53 Family and Cellular Stress Responses in Cancer.Targeting p53 by small molecules in hematological malignancies.Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor.Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cellsPNT2258, a novel deoxyribonucleic acid inhibitor, induces cell cycle arrest and apoptosis via a distinct mechanism of action: a new class of drug for non-Hodgkin's lymphoma.Ubiquitination in disease pathogenesis and treatment.Nutlin-3, A P53-Mdm2 Antagonist For Nasopharyngeal Carcinoma Treatment.Major apoptotic mechanisms and genes involved in apoptosis.αB-crystallin complexes with 14-3-3ζ to induce epithelial-mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma.Induction of apoptosis in Ehrlich ascites tumour cells via p53 activation by a novel small-molecule MDM2 inhibitor - LQFM030.
P2860

HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas.

Item
http://www.wikidata.org/entity/Q36323374
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
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2012年學術文章
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2012年學術文章
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name
HDM2 antagonist MI-219 (spiro- ...... an malignant B-cell lymphomas.
@ast
HDM2 antagonist MI-219 (spiro- ...... an malignant B-cell lymphomas.
@en
type
label
HDM2 antagonist MI-219 (spiro- ...... an malignant B-cell lymphomas.
@ast
HDM2 antagonist MI-219 (spiro- ...... an malignant B-cell lymphomas.
@en
prefLabel
HDM2 antagonist MI-219 (spiro- ...... an malignant B-cell lymphomas.
@ast
HDM2 antagonist MI-219 (spiro- ...... an malignant B-cell lymphomas.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P478
P577
P5875
P6179
P698
P921
P932
P356
P1433
P1476
HDM2 antagonist MI-219 (spiro- ...... an malignant B-cell lymphomas.
@en
P2093
P2860
P2888
P304
P31
P356
P478
P577
P5875
P6179
P698
P921
P932