Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling

Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling

Item
http://www.wikidata.org/entity/Q36325901
A mosaic activating mutation in AKT1 associated with the Proteus syndromeImpact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice.Establishment of a murine epidermal cell line suitable for in vitro and in vivo skin modellingDefining the origins of Ras/p53-mediated squamous cell carcinomaMsx2 and Foxn1 regulate nail homeostasis.The thyroid hormone receptors as modulators of skin proliferation and inflammationPI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer.Coactivator MED1 ablation in keratinocytes results in hair-cycling defects and epidermal alterations.A novel tumor suppressor network in squamous malignanciesA functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling.Transgenic mice expressing constitutively active Akt in oral epithelium validate KLFA as a potential biomarker of head and neck squamous cell carcinoma.Akt signaling leads to stem cell activation and promotes tumor development in epidermis.Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis.
P2860

Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling

Item
http://www.wikidata.org/entity/Q36325901
description
2007 nî lūn-bûn
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2007年の論文
@ja
2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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Constitutively active Akt indu ...... orphogenetic protein signaling
@ast
Constitutively active Akt indu ...... orphogenetic protein signaling
@en
type
label
Constitutively active Akt indu ...... orphogenetic protein signaling
@ast
Constitutively active Akt indu ...... orphogenetic protein signaling
@en
prefLabel
Constitutively active Akt indu ...... orphogenetic protein signaling
@ast
Constitutively active Akt indu ...... orphogenetic protein signaling
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Constitutively active Akt indu ...... orphogenetic protein signaling
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932