The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate
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Physiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous systemNeuroserpin Differentiates Between Forms of Tissue Type Plasminogen Activator via pH Dependent Deacylation.Proteolysis of proBDNF is a key regulator in the formation of memoryPhosphacan short isoform, a novel non-proteoglycan variant of phosphacan/receptor protein tyrosine phosphatase-beta, interacts with neuronal receptors and promotes neurite outgrowthNeuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cellsInvolvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitisSubacute intranasal administration of tissue plasminogen activator promotes neuroplasticity and improves functional recovery following traumatic brain injury in ratsValproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activityRegulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independentTissue plasminogen activator is a potent activator of PDGF-CCFibrinogen α-chain-derived peptide is upregulated in hippocampus of rats exposed to acute morphine injection and spontaneous alternation testing.Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons.Increasing tPA activity in astrocytes induced by multipotent mesenchymal stromal cells facilitate neurite outgrowth after stroke in the mousePlasmin-dependent modulation of the blood-brain barrier: a major consideration during tPA-induced thrombolysis?Tissue plasminogen activator and seizures: a clot-buster's secret life.Plasminogen deficiency causes reduced corticospinal axonal plasticity and functional recovery after stroke in mice.Treatment of TBI with collagen scaffolds and human marrow stromal cells increases the expression of tissue plasminogen activator.CRE-mediated transcription and COX-2 expression in the pilocarpine model of status epilepticus.Serine proteases regulating synaptic plasticity.Proteoglycans and injury of the central nervous system.Unmasking Proteolytic Activity for Adult Visual Cortex Plasticity by the Removal of Lynx1A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator.Extracellular proteolysis in structural and functional plasticity of mossy fiber synapses in hippocampusTissue-type plasminogen activator triggers the synaptic vesicle cycle in cerebral cortical neurons.Important role of matrix metalloproteinase 9 in epileptogenesis.Plasmin deficiency in Alzheimer's disease brains: causal or casual?Lectican proteoglycans, their cleaving metalloproteinases, and plasticity in the central nervous system extracellular microenvironment.Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia.tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2.Extracellular matrix in plasticity and epileptogenesis.Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules.Integrins as receptor targets for neurological disordersThe perineuronal net component of the extracellular matrix in plasticity and epilepsyRoles of matrix metalloproteinases and their targets in epileptogenesis and seizuresScar-modulating treatments for central nervous system injury.Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood.ADAMTS-4 in central nervous system pathologies.Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system.
P2860
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P2860
The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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name
The tissue plasminogen activat ...... rough a proteoglycan substrate
@ast
The tissue plasminogen activat ...... rough a proteoglycan substrate
@en
type
label
The tissue plasminogen activat ...... rough a proteoglycan substrate
@ast
The tissue plasminogen activat ...... rough a proteoglycan substrate
@en
prefLabel
The tissue plasminogen activat ...... rough a proteoglycan substrate
@ast
The tissue plasminogen activat ...... rough a proteoglycan substrate
@en
P2093
P2860
P356
P1476
The tissue plasminogen activat ...... rough a proteoglycan substrate
@en
P2093
J M Levine
M A Frohman
R U Margolis
S E Tsirka
P2860
P304
P356
10.1083/JCB.148.6.1295
P407
P577
2000-03-01T00:00:00Z