Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
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A halocin acting on Na+/H+ exchanger of haloarchaea as a new type of inhibitor in NHE of mammalsRegulation of cardiac sarcolemmal Na+/H+ exchanger activity by endogenous ligands. Relevance to ischemia.Na+/H+ exchangers. Molecular diversity and relevance to heart.Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice.Activity of the Na+/H+ exchanger contributes to cardiac damage following ischaemia and reperfusion.Pharmacological prevention of atrial tachycardia induced atrial remodeling as a potential therapeutic strategy.Intracellular Acid-extruding regulators and the effect of lipopolysaccharide in cultured human renal artery smooth muscle cells.Is timing everything? Therapeutic potential of modulators of cardiac Na(+) transporters.Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools.Na(+)/H(+) exchange and hypoxic pulmonary hypertension.Current perspectives of electrical remodeling and its therapeutic implications.Effect of Hoe 694, a novel Na(+)-H+ exchange inhibitor, on intracellular pH regulation in the guinea-pig ventricular myocyte.A novel antagonist, No. 7943, of the Na+/Ca2+ exchange current in guinea-pig cardiac ventricular cells.Sabiporide reduces ischemia-induced arrhythmias and myocardial infarction and attenuates ERK phosphorylation and iNOS induction in rats.Na+/H+ exchange and its inhibition in cardiac ischemia and reperfusion.Dose-dependent reduction of myocardial infarct mass in rabbits by the NHE-1 inhibitor cariporide (HOE 642).Role of intracellular Ca2+ and Na+/Ca2+ exchanger in the pathogenesis of contrast-induced acute kidney injury.Na+/H+ exchangers.Polyfluorinated groups in medicinal chemistry.Flow cytometric kinetic assay of the activity of Na+/H+ antiporter in mammalian cells.Alterations in sodium metabolism as an etiological model for hypertension.The p42/p44 mitogen-activated protein kinase cascade is determinant in mediating activation of the Na+/H+ exchanger (NHE1 isoform) in response to growth factors.The Na-H exchanger revisited: an update on Na-H exchange regulation and the role of the exchanger in hypertension and cardiac function in health and disease.S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.Effect of the Na+/H+ antiport inhibitor Hoe 694 on the angiotensin II-induced vascular smooth muscle cell growth.Alcoholism and carcinoma change the intracellular pH and activate platelet Na+/H+-exchange in men.Pharmacological profile of SL 59.1227, a novel inhibitor of the sodium/hydrogen exchanger.Effect of inhibitors of Na+/H+-exchange and gastric H+/K+ ATPase on cell volume, intracellular pH and migration of human polymorphonuclear leucocytes.Na(+)/H(+) exchange subtype 1 inhibition reduces endothelial dysfunction in vessels from stunned myocardium.Identification of sites in the second exomembrane loop and ninth transmembrane helix of the mammalian Na+/H+ exchanger important for drug recognition and cation translocation.Intracellular pH regulatory mechanism in human atrial myocardium: functional evidence for Na(+)/H(+) exchanger and Na(+)/HCO(3)(-) symporter.Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte.Adverse interactions of rofecoxib with lisinopril in spontaneously hypertensive rats.Functional diversity of electrogenic Na+-HCO3- cotransport in ventricular myocytes from rat, rabbit and guinea pig.HOE 694 affords protection versus veratrine contractures in rat atria by Na+ channel blockade.NBCe1 Na-HCO3 cotransporter ablation causes reduced apoptosis following cardiac ischemia-reperfusion injury
P2860
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P2860
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
@ast
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
@en
type
label
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
@ast
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
@en
prefLabel
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
@ast
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
@en
P2093
P2860
P1476
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
@en
P2093
B A Schölkens
H C Englert
P A Martorana
P2860
P304
P356
10.1111/J.1476-5381.1993.TB13607.X
P407
P577
1993-06-01T00:00:00Z