Absence of the cystic fibrosis transmembrane regulator (Cftr) from myeloid-derived cells slows resolution of inflammation and infection.
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Neutrophil plasticity enables the development of pathological microenvironments: implications for cystic fibrosis airway diseaseCystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectivesA neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.Neutrophil-mediated phagocytic host defense defect in myeloid Cftr-inactivated mice.Reactive-oxygen-species-mediated P. aeruginosa killing is functional in human cystic fibrosis macrophages.Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammationAnimal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology.Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy.Physiological impact of abnormal lipoxin A₄ production on cystic fibrosis airway epithelium and therapeutic potential.Partial Restoration of CFTR Function in cftr-Null Mice following Targeted Cell Replacement Therapy.Salt, chloride, bleach, and innate host defense.IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosisModulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.Increased susceptibility of Cftr-/- mice to LPS-induced lung remodeling.Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator.Cystic fibrosis transmembrane conductance regulator recruitment to phagosomes in neutrophils.Interleukin-17 Pathophysiology and Therapeutic Intervention in Cystic Fibrosis Lung Infection and Inflammation.A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis.Targeting cytosolic proliferating cell nuclear antigen in neutrophil-dominated inflammation.Azithromycin analogue CSY0073 attenuates lung inflammation induced by LPS challenge.Considerations for the Conduct of Clinical Trials with Antiinflammatory Agents in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report.Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells.Cystic Fibrosis Lung Immunity: The Role of the MacrophageFungal Pathogens in CF Airways: Leave or Treat?Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth.Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus.CFTR regulates acute inflammatory responses in macrophages.Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophagesExpression of soluble triggering receptor expressed on myeloid cells-1 in childhood CF and non-CF bronchiectasis.Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis.The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease.Optimal complement-mediated phagocytosis of Pseudomonas aeruginosa by monocytes is cystic fibrosis transmembrane conductance regulator-dependent.Neutrophil extracellular traps and the dysfunctional innate immune response of cystic fibrosis lung disease: a review.Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity.CFTR-dependent chloride efflux in cystic fibrosis mononuclear cells is increased by ivacaftor therapy.Macrophage Dysfunction in Cystic Fibrosis: A Therapeutic Target to Enhance Self-Immunity.Detection of CFTR protein in human leukocytes by flow cytometry.
P2860
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P2860
Absence of the cystic fibrosis transmembrane regulator (Cftr) from myeloid-derived cells slows resolution of inflammation and infection.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Absence of the cystic fibrosis ...... of inflammation and infection.
@ast
Absence of the cystic fibrosis ...... of inflammation and infection.
@en
type
label
Absence of the cystic fibrosis ...... of inflammation and infection.
@ast
Absence of the cystic fibrosis ...... of inflammation and infection.
@en
prefLabel
Absence of the cystic fibrosis ...... of inflammation and infection.
@ast
Absence of the cystic fibrosis ...... of inflammation and infection.
@en
P2093
P2860
P921
P356
P1476
Absence of the cystic fibrosis ...... of inflammation and infection.
@en
P2093
C A Hodges
C U Cotton
T L Bonfield
P2860
P304
P356
10.1189/JLB.0412188
P577
2012-08-02T00:00:00Z