Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin.
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Epigallocatechin-3-Gallate Accelerates Relaxation and Ca2+ Transient Decay and Desensitizes Myofilaments in Healthy and Mybpc3-Targeted Knock-in Cardiomyopathic Mice.Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy.Uncoupling of myofilament Ca2+ sensitivity from troponin I phosphorylation by mutations can be reversed by epigallocatechin-3-gallate.Sarcomere neutralization in inherited cardiomyopathy: small-molecule proof-of-concept to correct hyper-Ca2+-sensitive myofilamentsDesign, development, and characterization of lipid nanocarriers-based epigallocatechin gallate delivery system for preventive and therapeutic supplementation.Isolation and physiological analysis of mouse cardiomyocytes.Green tea extract catechin improves internal cardiac muscle relaxation in RCM mice.Molecular Defects in Cardiac Myofilament Ca2+-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin.Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF‑β1/Smad3 signaling pathway.(‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway.Hypertrophic cardiomyopathy mutations increase myofilament Ca2+ buffering, alter intracellular Ca2+ handling and stimulate Ca2+ dependent signalling.
P2860
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P2860
Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
Coordinated regulation of muri ...... the major green tea catechin.
@ast
Coordinated regulation of muri ...... the major green tea catechin.
@en
type
label
Coordinated regulation of muri ...... the major green tea catechin.
@ast
Coordinated regulation of muri ...... the major green tea catechin.
@en
prefLabel
Coordinated regulation of muri ...... the major green tea catechin.
@ast
Coordinated regulation of muri ...... the major green tea catechin.
@en
P2093
P2860
P356
P1476
Coordinated regulation of muri ...... the major green tea catechin.
@en
P2093
Asheesh K Tiwary
Birgit Puschner
Björn C Knollmann
Dmytro O Kryshtal
Hyun Seok Hwang
Isaac N Pessah
Isela T Padilla
P2860
P304
P356
10.1124/MOL.112.079707
P577
2012-08-23T00:00:00Z