Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers.
about
Peptide mimic of phosphorylcholine, a dominant epitope found on Streptococcus pneumoniaeThe autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysinHuman anti-phosphorylcholine antibodies share idiotopes and are self-binding.Induction of partial chimerism in nonirradiated B-lymphocyte-deficient CBA/N mice.Phosphorylcholine-specific helper T cells in mice with an X-linked defect of antibody production to the same hapten.Role of a nonimmunoglobulin cell surface determinant in the activation of B lymphocytes by thymus-independent antigensImmunoglobulin subclass-specific immunodeficiency in mice with an X-linked B-lymphocyte defect.Influence of the sex-linked defect in CBA/N mice on autoimmune responses to isologous erythrocytes. Ability to overcome the defect with age.Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression.Susceptibility to in vitro tolerance induction of adult B cells from mice with an X-linked B-cell defect.Subclass restriction of murine antibodies. II. The IgG plaque-forming cell response to thymus-independent type 1 and type 2 antigens in normal mice and mice expressing an X-linked immunodeficiency.Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. I. Mapping of genes for Id-460 expression to the variable region of immunoglobulin heavy-chain locus and to the variable region of immunoglobulin kappa-light-chAntiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniaeAntigen-specific helper T cells required for dominant idiotype expression are not H-2 restricted.Alteration of clonal profile. III. T15 ontogenetic advantages are not sufficient for establishing idiotypic dominance in adoptive transferAnti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.Immune response to a thymus-dependent form of B512 dextran requires the presence of Lyb-5+ lymphocytesIdiotype-recognizing T helper cells that are not idiotype specificSubpopulations of B cells distinguished by cell surface expression of Ia antigens. Correlation of Ia and idiotype during activation by cloned Ia-restricted T cellsInteraction of helper T cells and Lyb5+ B cells responding to phosphorylcholine is MHC-restricted.Characterization of murine antibody response to Salmonella typhimurium by a class-specific solid-phase radioimmunoassayStrong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae.Enhancement of mucosal antibody responses to Salmonella typhimurium and the microbial hapten phosphorylcholine in mice with X-linked immunodeficiency by B-cell precursors from the peritoneal cavity.X-linked immunodeficient mice exhibit enhanced susceptibility to Cryptococcus neoformans Infection.The adaptive potential of the memory response: clonal recruitment and epitope recognition.Functional and molecular studies of V genes expressed in autoantibodies.Repertoire expression in surface immunoglobulin-negative bone marrow B cell precursors.B cells: subpopulations, tolerance, autoimmunity, and infection.Murine models of tolerance induction in developing and mature B cells.Differences in virulence for mice among Streptococcus pneumoniae strains of capsular types 2, 3, 4, 5, and 6 are not attributable to differences in pneumolysin production.DBA/2Ha mice as a model of an X-linked immunodeficiency which is defective in the expression of TRF-acceptor site(s) on B lymphocytes.Induction of in vivo antipolysaccharide immunoglobulin responses to intact Streptococcus pneumoniae is more heavily dependent on Btk-mediated B-cell receptor signaling than antiprotein responses.
P2860
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P2860
Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers.
description
1977 nî lūn-bûn
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1977年の論文
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1977年学术文章
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1977年学术文章
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1977年学术文章
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1977年学术文章
@zh-my
1977年学术文章
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1977年學術文章
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1977年學術文章
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1977年學術文章
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name
Inability of mice with a defec ...... oline on immunogenic carriers.
@ast
Inability of mice with a defec ...... oline on immunogenic carriers.
@en
type
label
Inability of mice with a defec ...... oline on immunogenic carriers.
@ast
Inability of mice with a defec ...... oline on immunogenic carriers.
@en
prefLabel
Inability of mice with a defec ...... oline on immunogenic carriers.
@ast
Inability of mice with a defec ...... oline on immunogenic carriers.
@en
P2093
P2860
P356
P1476
Inability of mice with a defec ...... oline on immunogenic carriers.
@en
P2093
P2860
P304
P356
10.1084/JEM.146.4.1138
P407
P577
1977-10-01T00:00:00Z