Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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2012 nî lūn-bûn

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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P1476

Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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Jay V Patankar

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Michele Battle

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Sanja Levak-Frank

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Sascha Obrowsky

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Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice

Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine

Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development

AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

GATA4 is essential for jejunal function in mice

Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat.

Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities.

Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes.

Hepatic fibrosis--role of hepatic stellate cell activation.

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1061-1068

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scholarly article

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10.1016/J.JHEP.2012.06.028

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P478

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Dagmar Kratky

Gerald Hoefler

Prakash Doddapattar

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2012-06-28T00:00:00Z

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228102140

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22750465

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3477492

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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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P2860

P2860

Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

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name

type

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932