Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction - Wikidata - awgldk - TriplyDB

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

http://www.wikidata.org/entity/Q36342946

about

Epithelial Anion Transport as Modulator of Chemokine Signaling Store-operated Ca2+ channels in airway epithelial cell function and implications for asthma Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases The cell biology of asthma Antagonists of the TMEM16A calcium-activated chloride channel modulate airway smooth muscle tone and intracellular calcium.Protective effects of the polyphenol sesamin on allergen-induced T(H)2 responses and airway inflammation in mice Respiratory epithelial cells orchestrate pulmonary innate immunity.A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid Cellular functions of TMEM16/anoctamin Airway Gland Structure and Function Calmodulin regulation of TMEM16A and 16B Ca(2+)-activated chloride channels Inhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell Lines Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2 Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker Variomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation.17β-Estradiol inhibits phosphorylation of stromal interaction molecule 1 (STIM1) protein: implication for store-operated calcium entry and chronic lung diseases.Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle.Spontaneous Activity of Cochlear Hair Cells Triggered by Fluid Secretion Mechanism in Adjacent Support Cells.Acidic amino acids in the first intracellular loop contribute to voltage- and calcium- dependent gating of anoctamin1/TMEM16A.The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis Native small airways secrete bicarbonate.Calcium-calmodulin does not alter the anion permeability of the mouse TMEM16A calcium-activated chloride channel.Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium.A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity.Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists Modulating Ca²⁺ signals: a common theme for TMEM16, Ist2, and TMC.Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility.Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels Secreted CLCA1 modulates TMEM16A to activate Ca(2+)-dependent chloride currents in human cells.Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels.TMEM16A-Mediated Mucin Secretion in IL-13-Induced Nasal Epithelial Cells From Chronic Rhinosinusitis Patients.Molecular and functional significance of Ca(2+)-activated Cl(-) channels in pulmonary arterial smooth muscle.Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer.TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-β signaling.Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium Effects of new-generation inhibitors of the calcium-activated chloride channel anoctamin 1 on slow waves in the gastrointestinal tract.

P2860

Q26744381-795F915B-D488-4BCD-94F1-D922B47A34EA Q26744698-83834635-CCA0-496E-9229-026DC080D358 Q26776407-78FC6781-2387-4EC8-9A73-B33AEA2E4A25 Q27009449-D70F4CEB-5ACC-4B1A-B8E9-42255A9771F0 Q27318373-F4D0265C-B763-4497-99C8-921416E69CEE Q27335104-2941F834-D62D-482E-A82C-AC62399264E3 Q27687743-59B11A02-E575-4970-9C82-EAD9705DCC85 Q28066190-E45CEA3A-2C7A-46BE-BD66-E3F9EA017F64 Q28077344-5D1621BE-9023-4723-9DE0-ACAD808264EF Q28082284-6EC1F829-6E0B-4E16-B053-E3F22838B2F3 Q28084987-227306E2-8C0A-4035-BD82-29874C393F6D Q28546722-0B5B6F9F-9515-4E78-BAD4-1C8C87356B9E Q28552360-740FDDD6-69F9-4B5E-9B5B-4F7C36B4DE30 Q28566050-1B64BD4F-13F7-4B93-890E-0FFA49EC4098 Q28581384-FA8D8148-8874-40A6-B61D-4103C2AA7CD0 Q28601949-18E7EDDC-9151-434A-9836-8550A262BF0C Q30368943-20A68977-8988-47E4-B5F6-E18ADDFED84E Q30409431-4BAF095B-AE24-4298-A3A0-0E0336B3C4DE Q30664603-55DBF651-B100-4946-8114-453B4257BA1F Q30686396-6E2D468A-1645-493E-BB58-C4E511E77747 Q31164523-89EBE096-C48D-4B66-9C90-CF899DF18908 Q33685673-4798122A-05FB-42D3-A91B-75DB7F4DCBD2 Q33799611-238AE9C6-0C14-41CE-8E63-66BDC9CADF1A Q33826790-9B605EC7-6971-4521-8DD0-4CB945AEDD30 Q33856635-17E27E45-64E3-4F35-9EFD-FFF6429E0611 Q33957044-FB15E0B6-7DAE-4CD4-8346-11E3BE27258F Q34001667-E8C80494-AE41-49EA-9008-D22A9A2C92B4 Q34506445-32A61BD9-1B11-4977-87F9-0C63D9300C95 Q34519336-DB4384D9-6E20-429E-AB65-7BCAAC3AC1BF Q34620521-D31D5D3A-394D-4014-877C-D44A2614E2EC Q34793392-A99169D9-1121-4D87-B1E1-ADECBB642E83 Q35179521-1B080ABC-8639-4762-9C02-B5125716F66F Q35212659-084CA9EC-35EA-4757-9B7C-9F91F686BCD2 Q35657573-73B12AF5-8340-45F0-A42A-877813334689 Q35665725-376D4F30-3454-4E1C-A1D5-C0F3455BFD6A Q35677294-313CEE16-2826-49CC-BDC0-412E495AD8F7 Q35754730-B2A067E4-3DB8-48DF-9584-EDE8C3C0B75B Q35793867-D3743637-2074-4333-A969-DB6872AC2EDF Q35851705-A3923DCB-4A25-4630-B992-F6F54C7EF315 Q35895873-43CE7D4E-E7E4-40BB-9A8E-7AE70D93FC22

P2860

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

http://www.wikidata.org/entity/Q36342946

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Calcium-activated chloride cha ...... rway smooth muscle contraction

@ast

Calcium-activated chloride cha ...... rway smooth muscle contraction

@en

type

label

Calcium-activated chloride cha ...... rway smooth muscle contraction

@ast

Calcium-activated chloride cha ...... rway smooth muscle contraction

@en

prefLabel

Calcium-activated chloride cha ...... rway smooth muscle contraction

@ast

Calcium-activated chloride cha ...... rway smooth muscle contraction

@en

P1433

Q36342946-7A1E68DB-F680-4C3D-8628-D089EEE6CE54

P1476

Q36342946-3D0224BA-8753-4EAE-BE55-B3777A760CE5

P2093

Q36342946-0370E17A-CB5D-4910-A500-EED3E3949486

Q36342946-0BD7EBE6-1B68-4371-85EE-20D8852B6031

Q36342946-1529A56C-A6B1-4CCA-B938-59ACD19191E8

Q36342946-20C8C916-628B-4C40-BCC2-2674CD140060

Q36342946-22A75AF5-C6DE-4E9F-978B-68134BC03140

Q36342946-2B0FAC0D-B3D1-4822-B4F1-27240B513A69

Q36342946-352689C7-69CE-4E21-B6B6-1C3959F68331

Q36342946-54ECF01A-570A-4B56-8014-61C9BAF7324D

Q36342946-68BE734F-E059-4D48-BCDC-EA805E17A43F

Q36342946-87EA899B-19BB-497A-948A-6C735CA2B4EC

P2860

Q36342946-003A8636-75F4-46FB-9220-DB9BBDC66F45

Q36342946-02C51543-220C-4CB4-AD9C-9A1CAD270DE9

Q36342946-04A536B7-E0AD-4F38-8766-1747A05A8AE4

Q36342946-0613BF92-8936-4BEA-A8AA-4AD88708B3BF

Q36342946-0F1D8C08-4E1E-44DD-BD3F-AC53BB9306F1

Q36342946-1139755B-8ED1-419A-B172-89F867D83EA3

Q36342946-1189DC21-9E82-4254-A86B-DF40C2154646

Q36342946-1640A505-55D1-4A6E-87D4-FA2159D75733

Q36342946-1C301909-DE4F-4232-A963-FC29BC7C1DEF

Q36342946-1C6F0E74-B649-4AB1-B54F-390BAB95EE28

P304

Q36342946-1A9ADEF5-1A75-4F30-AE78-23E22F0E1381

P31

Q36342946-2384B3D3-43F9-4971-A245-88E7AE4CD9CC

P356

Q36342946-9432A605-28D6-467E-81EC-F6E16ECB4EF9

P407

Q36342946-A9B4177B-1B01-4859-BDC6-4962F1A8A740

P433

Q36342946-D817A1C6-8FB5-4FC9-9479-9D54D5B76694

P478

Q36342946-5CC278DA-724B-46BF-846F-29E1E1D2B096

P50

Q36342946-B4393CD7-D7AA-4593-9173-3A6A49C15C74

P577

Q36342946-06382D9F-CA17-4547-A2DA-263481819E42

P5875

Q36342946-92FFE227-C729-4F72-A59B-C533EF147F01

P698

Q36342946-6C00F128-6370-486C-BCAE-6849C37B70F7

P932

Q36342946-02CA95CE-4BE7-49A4-98D7-A462FCA9C1F0

P356

PNAS.1214596109

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Calcium-activated chloride cha ...... rway smooth muscle contraction

@en

P2093

Brigid L M Hogan

http://www.w3.org/2001/XMLSchema#string

Christian J Peters

http://www.w3.org/2001/XMLSchema#string

Dean Sheppard

http://www.w3.org/2001/XMLSchema#string

Fen Huang

http://www.w3.org/2001/XMLSchema#string

Hongkang Zhang

http://www.w3.org/2001/XMLSchema#string

Jason R Rock

http://www.w3.org/2001/XMLSchema#string

John V Fahy

http://www.w3.org/2001/XMLSchema#string

Lily Yeh Jan

http://www.w3.org/2001/XMLSchema#string

Makoto Kudo

http://www.w3.org/2001/XMLSchema#string

Matthew L Donne

http://www.w3.org/2001/XMLSchema#string

P2860

VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cells

Efficacy of allopurinol and benzbromarone for the control of hyperuricaemia. A pathogenic approach to the treatment of primary chronic gout

TMEM16A confers receptor-activated calcium-dependent chloride conductance

The role of CLCA proteins in inflammatory airway disease

Influenza H5N1 and H1N1 virus replication and innate immune responses in bronchial epithelial cells are influenced by the state of differentiation.

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Studies on expression and function of the TMEM16A calcium-activated chloride channel.

Mechanism and cellular applications of a green fluorescent protein-based halide sensor.

Green fluorescent protein-based halide indicators with improved chloride and iodide affinities.

Niflumic acid and MSI-2216 reduce TNF-alpha-induced mucin expression in human airway mucosa.

P304

16354-16359

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1214596109

http://www.w3.org/2001/XMLSchema#string

P407

P433

40

http://www.w3.org/2001/XMLSchema#string

P478

109

http://www.w3.org/2001/XMLSchema#string

P50

P577

2012-09-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

230871898

http://www.w3.org/2001/XMLSchema#string

P698

22988107

http://www.w3.org/2001/XMLSchema#string

P932

3479591

http://www.w3.org/2001/XMLSchema#string