Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
about
Administration of superantigens protects mice from lethal Listeria monocytogenes infection by enhancing cytotoxic T cells.Activated B cells can deliver help for the in vitro generation of antiviral cytotoxic T cells.Involvement of CD4(+) Th1 cells in systemic immunity protective against primary and secondary challenges with Trypanosoma cruzi.Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host diseaseDevelopment of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans.Multiple pathways of T-T interaction in the generation of cytotoxic T lymphocytes to alloantigens.Effect of helper T cells on the primary in vitro production of delayed-type hypersensitivity to influenza virus.Analysis of H-2 determinants recognized during the induction of H-Y-immune cytotoxic T cells by monoclonal antibodies in vitro.Helper activity is required for the in vivo generation of cytotoxic T lymphocytesHelper T cells for cytotoxic T lymphocytes need not be I region restricted.Requirement for three signals in B cell responses. II. Analysis of antigen- and Ia-restricted T helper cell-B cell interaction.Cytotoxic T lymphocyte nonresponsiveness to the male antigen H-Y in the H-2Db mutants bm13 and bm14. Complementation of the response in F1 crosses with the I-Ab mutant bm12 nonresponder and failure of B6 or Db mutant mice tolerant of each other to rThymus dictates major histocompatibility complex (MHC) specificity and immune response gene phenotype of class II MHC-restricted T cells but not of class I MHC-restricted T cells.Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection.Presentation of the H-Y antigen on Langerhans' cell-negative corneal grafts downregulates the cytotoxic T cell response and converts responder strain mice into phenotypic nonresponders.Susceptibility of human male keratinocytes to MHC-restricted H-Y-specific lysis.CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.In vivo priming of two distinct antitumor effector populations: the role of MHC class I expressionBone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes.Influence of H-2 antigen expression on killer T cell specificity, differentiation, and induction.H-2 restricted cytolytic and noncytolytic T cell clones: isolation, specificity and functional analysis.Lethal GVHD across minor histocompatibility barriers: nature of the effector cells and role of the H-2 complex.T cells, the MHC, and function.T-T cell interactions during cytotoxic T lymphocyte (CTL) responses: T cell derived helper factor (Interleukin 2) as a probe to analyze CTL responsiveness and thymic maturation of CTL progenitors.Lipopeptide-based melanoma cancer vaccine induced a strong MART-27-35-cytotoxic T lymphocyte response in a preclinal study.Hypothesis: immunological help is reciprocally delivered between different subpopulations of lymphocytes.Human minor histocompatibility antigens: new concepts for marrow transplantation and adoptive immunotherapy.Selection of cytotoxic T-cell precursors specific for minor histocompatibility determinants. I. Negative selection across H-2 barriers induced with disrupted cells but not with glutaraldehyde-treated cells: evidence for antigen processing.A methods paper that led to much more.Induction of cytotoxic T cell precursors in vivo. Role of T helper cellsThymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells.Negative selection of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers. Role of the H-2 complex.Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens.Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.Abortive activation precedes functional deletion of CD8+ T cells following encounter with self-antigens expressed by resting B cells in vivo.The generation and activation of memory class I MHC restricted cytotoxic T cell responses to influenza A virus in vivo do not require CD4+ T cells.Impaired generation of anti-viral cytotoxicity against lymphocytic choriomeningitis and vaccinia virus in mice treated with CD4-specific monoclonal antibody.Influence of CD4 T cells and the source of major histocompatibility complex class II-restricted peptides on cytotoxic T-cell priming by dendritic cells
P2860
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P2860
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
description
1979 nî lūn-bûn
@nan
1979年の論文
@ja
1979年学术文章
@wuu
1979年学术文章
@zh-cn
1979年学术文章
@zh-hans
1979年学术文章
@zh-my
1979年学术文章
@zh-sg
1979年學術文章
@yue
1979年學術文章
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1979年學術文章
@zh-hant
name
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
@ast
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
@en
type
label
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
@ast
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
@en
prefLabel
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
@ast
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
@en
P2860
P356
P1476
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen
@en
P2093
P2860
P304
P356
10.1084/JEM.150.5.1134
P407
P577
1979-11-01T00:00:00Z