about
SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomasInteractome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactorIntegrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexesThe insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growthTargeting mTOR for the treatment of AML. New agents and new directionsDe novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromesTargeting the PI3K signaling pathway in cancerBrick by brick: metabolism and tumor cell growthGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsGenomic characterization of esophageal squamous cell carcinoma: Insights from next-generation sequencingPI3K/Akt/mTOR inhibitors in breast cancerTargeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?Reviving Lonidamine and 6-Diazo-5-oxo-L-norleucine to Be Used in Combination for Metabolic Cancer TherapyA novel MMP-2 inhibitor 3-azidowithaferin A (3-azidoWA) abrogates cancer cell invasion and angiogenesis by modulating extracellular Par-4Targeted Therapies for Brain Metastases from Breast CancerWill targeting PI3K/Akt/mTOR signaling work in hematopoietic malignancies?Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesisPI3K and cancer: lessons, challenges and opportunitiesDirect positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase.The determinants of head and neck cancer: Unmasking the PI3K pathway mutationsBreast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane rufflingPRK1 distribution in normal tissues and carcinomas: overexpression and activation in ovarian serous carcinoma.Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells.Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models.Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancerEffective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitorEffects of novel isoform-selective phosphoinositide 3-kinase inhibitors on natural killer cell function.FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.PIK3CA mutations and copy number gains in human lung cancers.Highly frequent promoter methylation and PIK3CA amplification in non-small cell lung cancer (NSCLC).Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expressionInhibition of Akt with small molecules and biologics: historical perspective and current status of the patent landscape.PIK3CA gene mutations and overexpression: implications for prognostic biomarker and therapeutic target in Chinese esophageal squamous cell carcinoma.PIK3CA mutations in in situ and invasive breast carcinomas.Constitutive AKT activation in follicular lymphoma.Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alphaDiagnostic application of PIK3CA mutation analysis in Chinese esophageal cancer patients.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Oncogenic PI3K and its role in cancer.
@ast
Oncogenic PI3K and its role in cancer.
@en
type
label
Oncogenic PI3K and its role in cancer.
@ast
Oncogenic PI3K and its role in cancer.
@en
prefLabel
Oncogenic PI3K and its role in cancer.
@ast
Oncogenic PI3K and its role in cancer.
@en
P1476
Oncogenic PI3K and its role in cancer.
@en
P2093
Kajsa Ericson
Yardena Samuels
P356
10.1097/01.CCO.0000198021.99347.B9
P577
2006-01-01T00:00:00Z