CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model.
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Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinomaAntileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy.Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic MalignanciesDifferential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy.Dynamic chemotherapy-induced upregulation of CXCR4 expression: a mechanism of therapeutic resistance in pediatric AML.Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia.Targeting the CXCL12/CXCR4 axis in acute myeloid leukemia: from bench to bedside.Role of CXCR4 in the pathogenesis of acute myeloid leukemia.The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets.Cancer stem cells in haematological malignancies.Are there any new insights for G-CSF and/or AMD3100 in chemotherapy of haematological malignants?Targeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143).CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent mannerThe CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.Role of the microenvironment in myeloid malignancies.TGF-β1 and CXCL12 modulate proliferation and chemotherapy sensitivity of acute myeloid leukemia cells co-cultured with multipotent mesenchymal stromal cells.Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid LeukemiaEngraftment of chronic myelomonocytic leukemia cells in immunocompromised mice supports disease dependency on cytokines
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P2860
CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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name
CXCR4 inhibitors selectively e ...... emia cells in NOG mouse model.
@ast
CXCR4 inhibitors selectively e ...... emia cells in NOG mouse model.
@en
type
label
CXCR4 inhibitors selectively e ...... emia cells in NOG mouse model.
@ast
CXCR4 inhibitors selectively e ...... emia cells in NOG mouse model.
@en
prefLabel
CXCR4 inhibitors selectively e ...... emia cells in NOG mouse model.
@ast
CXCR4 inhibitors selectively e ...... emia cells in NOG mouse model.
@en
P2093
P2860
P50
P356
P1476
CXCR4 inhibitors selectively e ...... kemia cells in NOG mouse model
@en
P2093
F Pasquier
H Abdelouahab
S De Botton
P2860
P356
10.1038/CDDIS.2012.137
P577
2012-10-04T00:00:00Z