Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease - Wikidata - awgldk - TriplyDB

Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease

Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease

http://www.wikidata.org/entity/Q36347400

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The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice Impairment of the nerve growth factor pathway driving amyloid accumulation in cholinergic neurons: the incipit of the Alzheimer's disease story?Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice.The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease Neuropathology Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease.Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.Determination of amino acid neurotransmitters in rat hippocampi by HPLC-UV using NBD-F as a derivative.Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology Hippocampal plasticity during the progression of Alzheimer's disease.Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease.Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment Braak stage and trajectory of cognitive decline in noncognitively impaired elders.NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.Effects of acupuncture at HT7 on glucose metabolism in a rat model of Alzheimer's disease: an 18F-FDG-PET study The Inorganic Side of NGF: Copper(II) and Zinc(II) Affect the NGF Mimicking Signaling of the N-Terminus Peptides Encompassing the Recognition Domain of TrkA Receptor.ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic Mice Sorting receptor sortilin-a culprit in cardiovascular and neurological diseases.Low-Molecular-Weight NGF Mimetic Corrects the Cognitive Deficit and Depression-like Behavior in Experimental Diabetes.Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy.Amyloid β attenuates metabotropic zinc sensing receptor, mZnR/GPR39, dependent Ca2+ , ERK1/2 and Clusterin signaling in neurons.Molecular and cellular pathophysiology of preclinical Alzheimer's disease.Non-Demented Individuals with Alzheimer's Disease Neuropathology: Resistance to Cognitive Decline May Reveal New Treatment Strategies.Cerebral Glucose Metabolism Assessment in Rat Models of Alzheimer's Disease: An 18F-FDG-PET Study.The role of general anesthetics and the mechanisms of hippocampal and extra-hippocampal dysfunctions in the genesis of postoperative cognitive dysfunction.Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease.β-Ecdysterone protects SH-SY5Y cells against β-amyloid-induced apoptosis via c-Jun N-terminal kinase- and Akt-associated complementary pathways.Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-β (Aβ)42 peptides.Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease.Up-regulation of sortilin mediated by amyloid-β and p75(NTR): safety lies in the middle course.The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.

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Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease

http://www.wikidata.org/entity/Q36347400

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Hippocampal proNGF signaling p ...... pairment and Alzheimer disease

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Bin He

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Elliott J Mufson

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James Lah

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Jason Fritz

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Joanne Wuu

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Muhammad Nadeem

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Scott E Counts

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Stephen D Ginsberg

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Stephen W Scheff

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Sylvia E Perez

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P2860

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.

Sortilin is essential for proNGF-induced neuronal cell death

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

Mild cognitive impairment: pathology and mechanisms.

Neuropathological stageing of Alzheimer-related changes

Neurotrophin signal transduction in the nervous system.

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

Neuropathologic features of amnestic mild cognitive impairment

NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death

Statistical Methods in Medical Research

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23095849

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Alzheimer's disease

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3481187

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