The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1.
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The Hippo signal transduction network for exercise physiologistsA splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferationmiR-375 induces docetaxel resistance in prostate cancer by targeting SEC23A and YAP1.The role of extracellular biophysical cues in modulating the Hippo-YAP pathway.Promotion Effects of miR-375 on the Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells.Hippo Pathway and Skeletal Muscle Mass Regulation in Mammals: A Controversial Relationship.TGFβ1-induced leucine limitation uncovered by differential ribosome codon reading.The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and GrowthHypoxia and cellular metabolism in tumour pathophysiology.Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.Monoacylglycerol Lipase: A Novel Potential Therapeutic Target and Prognostic Indicator for Hepatocellular Carcinoma.Perspective: The Potential Role of Essential Amino Acids and the Mechanistic Target of Rapamycin Complex 1 (mTORC1) Pathway in the Pathogenesis of Child Stunting.Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growthYAP/TAZ-mediated activation of serine metabolism and methylation regulation is critical for LKB1-deficient breast cancer progression.An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops.Regulation of Tissue Growth by the Mammalian Hippo Signaling Pathway.FTY720-induced endocytosis of yeast and human amino acid transporters is preceded by reduction of their inherent activity and TORC1 inhibition.The polycystic ovary syndrome-associated gene Yap1 is regulated by gonadotropins and sex steroid hormones in hyperandrogenism-induced oligo-ovulation in mouse.Integrin-FAK-CDC42-PP1A signaling gnaws at YAP/TAZ activity to control incisor stem cells.Phosphorylated mTOR and YAP serve as prognostic markers and therapeutic targets in gliomas.The Role of Hippo Pathway in Cancer Stem Cell Biology.Mesenchymal Stem Cells Enhance Liver Regeneration via Improving Lipid Accumulation and Hippo Signaling.The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health.Epithelioid Hemangioendothelioma as a Model of YAP/TAZ-Driven Cancer: Insights from a Rare Fusion SarcomaGlutamine-utilizing transaminases are a metabolic vulnerability of TAZ/YAP-activated cancer cells
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The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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name
The Hippo pathway effectors YA ...... mino acid signaling to mTORC1.
@ast
The Hippo pathway effectors YA ...... mino acid signaling to mTORC1.
@en
type
label
The Hippo pathway effectors YA ...... mino acid signaling to mTORC1.
@ast
The Hippo pathway effectors YA ...... mino acid signaling to mTORC1.
@en
prefLabel
The Hippo pathway effectors YA ...... mino acid signaling to mTORC1.
@ast
The Hippo pathway effectors YA ...... mino acid signaling to mTORC1.
@en
P2093
P2860
P356
P1433
P1476
The Hippo pathway effectors YA ...... amino acid signaling to mTORC1
@en
P2093
Kun-Liang Guan
Steven W Plouffe
Wai-Ling Macrina Lam
Yuen Lam Dora Ng
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P2888
P304
P356
10.1038/CR.2015.140
P577
2015-11-27T00:00:00Z