TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes
about
Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and maps to chromosome 1q21-23Ly6 family proteins in neutrophil biologyCloning and expression of a cDNA for the T-cell-activating protein TAPIsolation of a murine Ly-6 cDNA reveals a new multigene family.Costimulatory signal provided by a B-lymphoblastoid cell line and its Ia-negative variant.B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cellsMurine Ly-6 multigene family is located on chromosome 15Biosynthesis, glycosylation, and partial N-terminal amino acid sequence of the T-cell-activating protein TAP.Mouse stem cell antigen Sca-2 is a member of the Ly-6 family of cell surface proteinsDifferential expression of glycosylphosphatidylinositol-anchored proteins in a murine T cell hybridoma mutant producing limiting amounts of the glycolipid core. Implications for paroxysmal nocturnal hemoglobinuria.Gene encoding T-cell-activating protein TAP maps to the Ly-6 locus.Investigating B Cell Development, Natural and Primary Antibody Responses in Ly-6A/Sca-1 Deficient MiceLy-6C regulates endothelial adhesion and homing of CD8(+) T cells by activating integrin-dependent adhesion pathways.The glycosyl phosphatidylinositol-linked Fc gamma RIIIPMN mediates transmembrane signaling events distinct from Fc gamma RII.Role of Ly-6 in lymphocyte activation. II. Induction of T cell activation by monoclonal anti-Ly-6 antibodiesDeficiency of lymphocyte function-associated antigen 3 (LFA-3) in paroxysmal nocturnal hemoglobinuria. Functional correlates and evidence for a phosphatidylinositol membrane anchor.Altered proliferative response by T lymphocytes of Ly-6A (Sca-1) null miceBiosynthesis of a phosphatidylinositol-glycan-linked membrane protein: signals for posttranslational processing of the Ly-6E antigen.Murine B7 antigen provides an efficient costimulatory signal for activation of murine T lymphocytes via the T-cell receptor/CD3 complex.Mice deficient in stem cell antigen-1 (Sca1, Ly-6A/E) develop normal primary and memory CD4+ and CD8+ T-cell responses to virus infection.Expression of T-cell-activating protein in peripheral lymphocyte subsets.Low temperature and peptides favor the formation of class I heterodimers on RMA-S cells at the cell surface.ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content.Accessory cell signals involved in T-cell activation.Activation of mouse T lymphocytes by a monoclonal antibody to a developmentally regulated surface aminopeptidase (THAM).Engaging Ly-6A/Sca-1 triggers lipid raft-dependent and -independent responses in CD4(+) T-cell lines.The LY-6 locus: a multigene family encoding phosphatidylinositol-anchored membrane proteins concerned with T-cell activation.Molecular and functional properties of novel T cell subsets in C3H-gld/gld and nude mice. Implications for thymic and extrathymic maturation.Promotion of cytotoxic T-cell generation in mixed leukocyte culture by phosphatidylinositol-specific phospholipase C from Bacillus thuringiensis.Membrane-associated proteins regulating the complement system: functions and deficiencies.Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol.Direct evidence of involvement of glycosylphosphatidylinositol-anchored proteins in the heavy metal-mediated signal delivery into T lymphocytes.Activation of rat T lymphocytes by anti-CD2 monoclonal antibodies.A monoclonal antibody (8H3) that binds to rat T lineage cells and augments in vitro proliferative responses.Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells.Genetic differences in bone marrow-derived lymphoid lineages control susceptibility to experimental autoimmune myocarditis.
P2860
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P2860
TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
TAP, a novel T cell-activating ...... f MHC-restricted T lymphocytes
@ast
TAP, a novel T cell-activating ...... f MHC-restricted T lymphocytes
@en
type
label
TAP, a novel T cell-activating ...... f MHC-restricted T lymphocytes
@ast
TAP, a novel T cell-activating ...... f MHC-restricted T lymphocytes
@en
prefLabel
TAP, a novel T cell-activating ...... f MHC-restricted T lymphocytes
@ast
TAP, a novel T cell-activating ...... f MHC-restricted T lymphocytes
@en
P2093
P2860
P356
P1476
TAP, a novel T cell-activating ...... f MHC-restricted T lymphocytes
@en
P2093
P2860
P304
P356
10.1084/JEM.163.2.315
P407
P577
1986-02-01T00:00:00Z