DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers
about
Structure of the thermally stable Zika virusDengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika VirusDissecting Virus Infectious Cycles by Cryo-Electron MicroscopyRapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell culturesDengue Fever: Causes, Complications, and Vaccine StrategiesRecent advances in understanding denguePrecisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody ResponsesDeconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and ImmunityDengue: an update on treatment optionsMapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to DENV4 Infection and VaccinationIdentifying Candidate Targets of Immune Responses in Zika Virus Based on Homology to Epitopes in Other Flavivirus SpeciesStructural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal AntibodyDengue: knowledge gaps, unmet needs, and research prioritiesAXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flavivirusesA single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesisThe Antigenic Structure of Zika Virus and Its Relation to Other Flaviviruses: Implications for Infection and ImmunoprophylaxisA human antibody against Zika virus crosslinks the E protein to prevent infectionHumoral cross-reactivity between Zika and dengue viruses: implications for protection and pathologyCovalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitopeTemperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells.In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers.Immune correlates for dengue vaccine developmentA new quaternary structure epitope on dengue virus serotype 2 is the target of durable type-specific neutralizing antibodies.Evolutionarily Successful Asian 1 Dengue Virus 2 Lineages Contain One Substitution in Envelope That Increases Sensitivity to Polyclonal Antibody Neutralization.Conformational changes in intact dengue virus reveal serotype-specific expansion.Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious CloneParadoxical role of antibodies in dengue virus infections: considerations for prophylactic vaccine development.Immune correlates of protection for dengue: State of the art and research agenda.New developments in flavivirus drug discovery.The Role of the Membrane in the Structure and Biophysical Robustness of the Dengue Virion Envelope.Molecular basis of antibody-mediated neutralization and protection against flavivirus.The mechanistic role of antibodies to dengue virus in protection and disease pathogenesis.AChiralPentagonalPolyhedralFramework forCharacterizingVirusCapsidStructures.Vaccines licensed and in clinical trials for the prevention of dengue.Genetic epidemiology of dengue viruses in phase III trials of the CYD tetravalent dengue vaccine and implications for efficacyComplexity of Human Antibody Response to Dengue Virus: Implication for Vaccine Development.Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design.Which Dengue Vaccine Approach Is the Most Promising, and Should We Be Concerned about Enhanced Disease after Vaccination? The Path to a Dengue Vaccine: Learning from Human Natural Dengue Infection Studies and Vaccine Trials.Dengue virus: Bumps in the road to therapeutic antibodies.Antimicrobials: Novel antibodies defeat dengue virus.
P2860
Q24082710-72B4A825-B82B-4F56-AA3C-444F58549902Q26247258-2E06EC83-78BB-4921-97B4-0AC0E1BE4325Q26700032-B7FF82B9-1520-4EA6-AD0E-C45C8AA74CC2Q26700070-28BEBDD4-CB00-4B5C-A4D3-A86BED95D7DEQ26700082-42AC677C-E476-4CB0-A2A7-D210DC7567FEQ26766156-71F3B17C-C4E1-41C2-8F9E-A6CBBA7FAC06Q27493140-F446D9E0-7B30-4DBD-9514-F1B45055B7A0Q27654848-95F7478B-01B7-4FAF-A656-AD2BE8BE39A7Q28085044-98E6CDEA-1B5F-4141-B13F-90F1FB2665D9Q28114614-8FB84C38-2FCD-4807-A494-4E2FC6868603Q28119651-1CDF7250-5C57-4633-9F34-0E95C1CE6316Q28550496-8EEE7D6D-0601-4DDA-99CB-37477EB0D420Q28729764-2E410CFF-3A53-471B-B023-5C2C80F4AB8DQ28729915-7A8B0E7A-3EB8-43BD-8BEF-05A2065E2903Q28804076-DF967C7C-B458-4970-9EB2-6885F2C72483Q28804225-5E39598D-2165-4E77-A483-DF9EBF8D0FAEQ28950443-1CCB96B7-2671-4545-B53C-694108FF6B1CQ29994510-0FED6075-8D9C-4C0B-86D6-DE5DEF880375Q30250932-B6C40616-32D7-450A-89FA-5F1491978C7FQ33681310-F94F57F4-1C5C-4FA5-B4ED-49539E834017Q33867337-8D7DE3B5-57F8-49D8-9A68-5054622DDABBQ33924674-B180EADA-8A00-4B50-82B2-4747E17F6D33Q36205859-2F42D202-CF41-4BE3-9A28-57B23FAE02E2Q36597801-F83541A6-36A5-48C6-8175-D174B10DD923Q37642687-123622D6-0CAC-4C67-83B7-A5CC5B4609CEQ37661008-0C9F3A65-AD6D-4E7F-B8A9-203988BF478BQ38636217-A6B16804-FD7F-4E5B-89CC-5F6E1ECB832CQ38652971-7A0596F5-5787-4B6E-871F-82E39E48D945Q38769771-13E807EE-E5B4-4F62-B353-9F9BD93232A7Q38816571-5F89EBF9-C542-49D7-AEFE-CC99B1EF307BQ38948606-BB1A1A07-70C1-4AED-9B3F-73A66C6899FBQ38994574-C553E412-FCE0-4879-936A-97F7303AA525Q39017347-AE548DF4-A3D2-4FD3-91BC-B8810132A39BQ39172722-C205CF3F-425B-4F2E-96BC-B4E95644F2C2Q39375868-3C6AD6F7-E3E4-4C87-85B5-C963DD6AD438Q39535403-7119AA2E-F898-4EA6-925D-D37AED91D240Q40043685-6A380B3E-8E80-43CB-B3EB-5256714902F1Q40047887-A9557D3D-1B15-41FE-B28F-DF31794444BCQ40142572-D8A6A7EA-FCF2-4DD1-9866-B65312B0D582Q40143286-9CCB1CB8-7B72-48C8-9DAD-2A0E7B8895A2
P2860
DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
DENGUE VIRUS. Cryo-EM structur ...... 2 by locking E protein dimers
@ast
DENGUE VIRUS. Cryo-EM structur ...... 2 by locking E protein dimers
@en
type
label
DENGUE VIRUS. Cryo-EM structur ...... 2 by locking E protein dimers
@ast
DENGUE VIRUS. Cryo-EM structur ...... 2 by locking E protein dimers
@en
prefLabel
DENGUE VIRUS. Cryo-EM structur ...... 2 by locking E protein dimers
@ast
DENGUE VIRUS. Cryo-EM structur ...... 2 by locking E protein dimers
@en
P2093
P2860
P50
P921
P356
P1433
P1476
DENGUE VIRUS. Cryo-EM structur ...... 2 by locking E protein dimers
@en
P2093
Jiaqi Wang
Joanne L Tan
Justin S G Ooi
Kristie D Ibarra
Scott A Smith
Shee-Mei Lok
Thiam-Seng Ng
P2860
P356
10.1126/SCIENCE.AAA8651
P407
P577
2015-07-01T00:00:00Z