Defective lymphopoiesis in bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. I. Analysis of development of prothymocytes, early B lineage cells, and terminal deoxynucleotidyl transferase-positive cells
about
Hematopoietic cell phosphatase, SHP-1, is constitutively associated with the SH2 domain-containing leukocyte protein, SLP-76, in B cellsIdentification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signalingThe tyrosine phosphatase SHP-1 influences thymocyte selection by setting TCR signaling thresholds.SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levelsLack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness.Increased negative selection impairs neonatal B cell repertoire but does not directly lead to generation of disease-associated IgM auto-antibodies.Murine "viable motheaten" mutation reveals a gene critical to the development of both B and T lymphocytesDefective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. III. Normal mouse bone marrow cells enable mev/mev prothymocytes to generate thymocytes after intravenous transferDepletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats.The CD5+ B cell: a B cell lineage with a central role in autoimmune disease?Molecular basis of the motheaten phenotype.Hematopoietic cell phosphatase is recruited to CD22 following B cell antigen receptor ligation.B cell development in mice.Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice.Regulation of the dephosphorylation of Stat6. Participation of Tyr-713 in the interleukin-4 receptor alpha, the tyrosine phosphatase SHP-1, and the proteasome.
P2860
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P2860
Defective lymphopoiesis in bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. I. Analysis of development of prothymocytes, early B lineage cells, and terminal deoxynucleotidyl transferase-positive cells
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Defective lymphopoiesis in bon ...... dyl transferase-positive cells
@ast
Defective lymphopoiesis in bon ...... dyl transferase-positive cells
@en
type
label
Defective lymphopoiesis in bon ...... dyl transferase-positive cells
@ast
Defective lymphopoiesis in bon ...... dyl transferase-positive cells
@en
prefLabel
Defective lymphopoiesis in bon ...... dyl transferase-positive cells
@ast
Defective lymphopoiesis in bon ...... dyl transferase-positive cells
@en
P2093
P2860
P356
P1476
Defective lymphopoiesis in bon ...... dyl transferase-positive cells
@en
P2093
D L Greiner
E S Medlock
F J Bollum
I Goldschneider
K L Komschlies
P2860
P304
P356
10.1084/JEM.164.4.1129
P407
P577
1986-10-01T00:00:00Z