A distinct wave of human T cell receptor gamma/delta lymphocytes in the early fetal thymus: evidence for controlled gene rearrangement and cytokine production
about
Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon,delta proteinsClose link between development and function of gamma-delta T cellsStructure of the Vdelta domain of a human gammadelta T-cell antigen receptorAntigen recognition by human gamma delta T cells: pattern recognition by the adaptive immune systemCellular immune responses in neonates.RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangementTissue distribution, antigen specificity and effector functions of gamma delta T cells in human diseases.Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoireRegulation and function of IL-17A- and IL-22-producing γδ T cells.Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity.Stem cell transplantation in the fetus.The delta T cell receptor repertoire in human colon and peripheral blood is oligoclonal irrespective of V region usageRegulation of the mature human T cell receptor gamma repertoire by biased V-J gene rearrangement.Clonal expansions of activated gamma/delta T cells in recent-onset multiple sclerosisEvidence for clonal selection of gamma/delta T cells in response to a human pathogen.Fetal liver T cell receptor gamma/delta+ T cells as cytotoxic T lymphocytes specific for maternal alloantigensTumor necrosis factor alpha is involved in mouse growth and lymphoid tissue development.Human fetal liver gamma/delta T cells predominantly use unusual rearrangements of the T cell receptor delta and gamma loci expressed on both CD4+CD8- and CD4-CD8- gamma/delta T cells.Peripheral selection of V delta 1+ cells with restricted T cell receptor delta gene junctional repertoire in the peripheral blood of healthy donors.Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers.Surface expression of functional T cell receptor chains formed by interlocus recombination on human T lymphocytes.Early human T cell development: analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironmentOntogenic development and tissue distribution of V gamma 1-expressing gamma/delta T lymphocytes in normal mice.Assembly of productive T cell receptor delta variable region genes exhibits allelic inclusionBiology of the human gamma delta T-cell receptor.Enhancer control of local accessibility to V(D)J recombinase.Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936.Chicken T-cell receptor beta-chain diversity: an evolutionarily conserved D beta-encoded glycine turn within the hypervariable CDR3 domainHuman γδT-cell subsets and their involvement in tumor immunity.Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells.Divergent evolution of T cell repertoires: extensive diversity and developmentally regulated expression of the sheep gamma delta T cell receptorPhenotypic and molecular characterization of human monoclonal TCR gamma/delta T-cell lines from jejunum and colon of healthy individuals.Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene.Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.Thymic selection of the human T cell receptor V beta repertoire in SCID-hu mice.Use of the V delta 1 variable region in the functional T-cell receptor alpha chain of a WT31+ cytotoxic T lymphocyte clone which specifically recognizes HLA-A2 molecule.RUNX1 as a recombinase cofactor.Preferential rearrangements of the V gamma I subgroup of the gamma-chain of the T-cell antigen receptor to J gamma 2C gamma 2 gene segments in peripheral blood lymphocyte transcripts from normal donors.Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
P2860
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P2860
A distinct wave of human T cell receptor gamma/delta lymphocytes in the early fetal thymus: evidence for controlled gene rearrangement and cytokine production
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
A distinct wave of human T cel ...... gement and cytokine production
@ast
A distinct wave of human T cel ...... gement and cytokine production
@en
type
label
A distinct wave of human T cel ...... gement and cytokine production
@ast
A distinct wave of human T cel ...... gement and cytokine production
@en
prefLabel
A distinct wave of human T cel ...... gement and cytokine production
@ast
A distinct wave of human T cel ...... gement and cytokine production
@en
P2093
P2860
P356
P1476
A distinct wave of human T cel ...... gement and cytokine production
@en
P2093
C Brocklehurst
M S Krangel
P2860
P304
P356
10.1084/JEM.172.3.847
P407
P577
1990-09-01T00:00:00Z