Initial events in the formation of immune deposits in passive Heymann nephritis. gp330-anti-gp330 immune complexes form in epithelial coated pits and rapidly become attached to the glomerular basement membrane.
about
Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterinFunctional domains of the receptor-associated protein (RAP)The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivoThe solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated proteinThe unfolding story of megalin (gp330): now recognized as a drug receptorMembranous nephropathy: not just a disease for adultsMetalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis.Autoimmunity in membranous nephropathy targets aldose reductase and SOD2.39-kD protein inhibits tissue-type plasminogen activator clearance in vivo.TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology.Experimental membranous nephropathy reduxMesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1Molecular cloning of a cDNA encoding a major pathogenic domain of the Heymann nephritis antigen gp330Autoantibodies to the laminin P1 fragment in HgCl2-induced membranous glomerulopathyComplete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family.Binding of monoclonal antibodies to glomerular endothelium, slit membranes, and epithelium after in vivo injection. Localization of antigens and bound IgGs by immunoelectron microscopy.Monoclonal antibodies against membrane proteins of the rat glomerulus. Immunochemical specificity and immunofluorescence distribution of the antigensA beta 1-integrin receptor for fibronectin in human kidney glomeruli.Role of dipeptidyl peptidase IV (gp 108) in passive Heymann nephritis. Use of dipeptidyl peptidase IV-deficient rats.Studies with antibodies to cultured rat glomerular epithelial cells. Subepithelial immune deposit formation after in vivo injectionLoss of antigens associated with the apical endocytotic pathway in proximal tubules from rats with heymann nephritisGlomerular basement membrane expansion in passive Heymann nephritis. Absence of increased synthesis of type IV collagen, laminin, or fibronectinDetection of two forms of GP330. Their role in Heymann nephritis.Immunocytochemical and biochemical characterization of the Heymann nephritis antigenic complex in rat L2 yolk sac cells.An evaluation of experimental models of glomerulonephritisIdentification of the second cluster of ligand-binding repeats in megalin as a site for receptor-ligand interactionsReactive oxygen species and neutrophil respiratory burst cytochrome b558 are produced by kidney glomerular cells in passive Heymann nephritis.Treatment of idiopathic membranous nephropathy.Identification of a cell line that expresses a cell surface and a soluble form of the gp330/receptor-associated protein (RAP) Heymann nephritis antigenic complexInduction of passive Heymann nephritis with antibodies specific for a synthetic peptide derived from the receptor-associated protein.Membranous Nephropathy: A Journey From Bench to Bedsidegp330 associates with a 44-kDa protein in the rat kidney to form the Heymann nephritis antigenic complex.Identification of a pathogenic epitope involved in initiation of Heymann nephritis.Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp330 in passive Heymann nephritis.Endocytic trafficking of megalin/RAP complexes: dissociation of the complexes in late endosomes.Mapping rat megalin: the second cluster of ligand binding repeats contains a 46-amino acid pathogenic epitope involved in the formation of immune deposits in Heymann nephritis.Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers2015 Homer W. Smith Award: The Podocyte from Periphery to Center Stage.A podocyte view of membranous nephropathy: from Heymann nephritis to the childhood human disease.Membranous nephropathy. Insights from Heymann nephritis.
P2860
Q24320176-0F2A6E25-2F79-4682-80EC-4483D9B80288Q24563643-02AAC3F2-C45B-4162-A522-A7308D83AB22Q24630259-75B88A4C-1DD7-45E5-8E3A-53C556C945B0Q24655055-F5463075-9DBA-4D9B-B388-F82943DDAFE0Q24679255-0B7F67AE-35BC-41FD-ACFC-6CE800A682A1Q26866206-DB181D22-4B65-462C-8C62-D45E1A261712Q33338489-8AD71FFC-4087-497D-BFE0-AB73EE626A0EQ33530824-EC140F06-A2CB-4593-B861-3E73373350C1Q34171709-46895EA0-AE94-4F2D-8029-9CE67E9ED1D9Q34211578-20B4EBE3-92D4-46A1-8B8B-3AFAF0B597E6Q34248969-B11F2A2A-281B-42C7-A9F8-AA0E6DD512B8Q34760635-FE184D94-EDCE-4AC6-8F19-85DEBCF75632Q35002628-89E84452-5A08-4C25-87F3-D36C98B7C6CFQ35798207-784967A0-843D-4118-A3AC-885D0E4E6925Q35809266-9CBE97D4-9E31-40CD-B3EF-9A28459489F0Q35811592-36D02F73-5720-48D7-B58C-84653FEB2696Q35811650-DC294C9C-515F-4FB5-9595-BC45377F1BDFQ35816160-677CC34B-395C-4DAB-AEBB-30E2C6A258A0Q35816179-34B35633-C762-44D6-91B0-D0D5FC194A2CQ35816847-779E3457-B104-4BAB-B510-4AA32B7701A4Q35830310-6B712E2F-EE70-43C2-BB76-3A31F8015247Q35830794-07597386-DBF5-4D83-A9DC-737A3B00CED4Q35833160-96C2AEC0-183C-411D-A483-8EE5796F7C86Q35833454-DB9C0293-3588-44CB-BA09-95C00008E10DQ36028168-B3EB6D78-AADB-437B-83FC-CB20E1B673CFQ36041570-DCC0B307-70AD-4674-8340-9122D257812BQ36256084-AD91A7E7-7DDC-4655-8A33-39544FA43DDCQ36280345-8681562B-F6F1-4746-A6AE-274BDAF9BCB1Q36280472-97F1B6B9-B6E8-45ED-B7A8-D940B204797CQ36366699-BA982E27-AFF1-4CD8-B665-9DA2EDD90485Q37038576-7BDDC17B-2364-4F0E-932D-802116958252Q37117198-AAE62AF3-3FF7-4617-A4AD-FCF85CB4A92CQ37312078-8890E48C-2468-4743-AFD8-6A82C552B1D1Q37374296-E2483414-67B5-4681-9598-7AD2220A302EQ37385257-0C05E33F-979D-4BC7-A8BE-AE13505B4E26Q37411916-0AA93AAA-4BF5-4293-AFE6-F34E5465AA04Q37633630-E58B57A2-5B59-4B7D-A9CE-3F157ED31FD4Q38871277-9156281E-76C5-4B3C-850A-F3E376E2615DQ39361330-55A099E4-5367-4839-B5D6-C64F5BC4F88AQ40741944-740B7D14-92E1-41B3-853B-270F3E8BCD6E
P2860
Initial events in the formation of immune deposits in passive Heymann nephritis. gp330-anti-gp330 immune complexes form in epithelial coated pits and rapidly become attached to the glomerular basement membrane.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Initial events in the formatio ...... glomerular basement membrane.
@ast
Initial events in the formatio ...... glomerular basement membrane.
@en
type
label
Initial events in the formatio ...... glomerular basement membrane.
@ast
Initial events in the formatio ...... glomerular basement membrane.
@en
prefLabel
Initial events in the formatio ...... glomerular basement membrane.
@ast
Initial events in the formatio ...... glomerular basement membrane.
@en
P2093
P2860
P356
P1476
Initial events in the formatio ...... glomerular basement membrane.
@en
P2093
A Miettinen
D Kerjaschki
M G Farquhar
P2860
P304
P356
10.1084/JEM.166.1.109
P407
P577
1987-07-01T00:00:00Z