Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)
about
Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance ProfilingThe many faces of the flavivirus NS5 protein in antagonism of type I interferon signalingLooking for inhibitors of the dengue virus NS5 RNA-dependent RNA-polymerase using a molecular docking approachStructures of NS5 Methyltransferase from Zika VirusThe Zika virus methyltransferase: structure and functions for drug design perspectivesThe clinically approved antiviral drug sofosbuvir inhibits Zika virus replicationThe crystal structure of Zika virus NS5 reveals conserved drug targetsDengue Virus Non-Structural Protein 5Development of a S-adenosylmethionine analog that intrudes the RNA-cap binding site of Zika methyltransferaseCrystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5.New developments in flavivirus drug discovery.A general method for rapid and cost-efficient large-scale production of 5' capped RNA.NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication.The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.
P2860
Q26247399-DE7193A9-F1F1-48B5-AA32-ACCC8FDD05CAQ27924714-0DBD272B-CD70-4CE8-8B47-AD6EB2E9E481Q27928028-4FE3B66D-59F4-49C9-ACF8-10B51A818380Q27928070-26F897FC-3A26-4ABF-9F52-4D8983A737E9Q28114691-75F52A8A-35E7-4C71-866E-D589A4B86A01Q28595139-0305A195-E594-4C08-B556-72C6239B024DQ29365336-939DED65-18A4-4F72-AC79-0D3A6F3CA2C1Q29994565-A80BACF2-A822-4289-A5EF-0E33D34E8D91Q30145632-407D9D36-23A9-4CB2-B469-5CBA2EB0C9E7Q37698482-EF959437-75CE-45E4-8984-AF2E8C501BF6Q38769771-9B047395-77ED-49D6-A62F-34A103F7B3F2Q40671228-11A58EAB-D16F-4439-AA9C-E90BFB9AB304Q45324413-75362631-2881-41C1-A2C3-296C6C4ED688Q49215219-C8B361D3-40BF-412C-A3E8-72C9402A9B39
P2860
Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Molecular basis for specific v ...... nonstructural protein 5 (NS5)
@ast
Molecular basis for specific v ...... nonstructural protein 5 (NS5)
@en
type
label
Molecular basis for specific v ...... nonstructural protein 5 (NS5)
@ast
Molecular basis for specific v ...... nonstructural protein 5 (NS5)
@en
prefLabel
Molecular basis for specific v ...... nonstructural protein 5 (NS5)
@ast
Molecular basis for specific v ...... nonstructural protein 5 (NS5)
@en
P2093
P2860
P50
P356
P1476
Molecular basis for specific v ...... nonstructural protein 5 (NS5)
@en
P2093
Julien Lescar
Ka Yan Chung
Kunchithapadam Swaminathan
Subhash G Vasudevan
Tingjin Sherryl Soh
Yongqian Zhao
P2860
P304
14834-14839
P356
10.1073/PNAS.1514978112
P407
P577
2015-11-17T00:00:00Z