Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2
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Targeted therapies for pancreatic adenocarcinoma: Where do we stand, how far can we go?Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.Roscovitine protects murine Leydig cells from lipopolysaccharide-induced inflammationTranscriptomic analysis of pancreatic cancer cells in response to metformin and aspirin: an implication of synergy.New-onset type 2 diabetes, elevated HbA1c, anti-diabetic medications, and risk of pancreatic cancer.N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins.Metformin reduces gastric cancer risk in patients with type 2 diabetes mellitus.Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instability in vivoGermline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.Natural Products as Adjunctive Treatment for Pancreatic Cancer: Recent Trends and Advancements.Metformin use and cervical cancer risk in female patients with type 2 diabetesProteomic modulation in breast tumors after metformin exposure: results from a "window of opportunity" trial.The expanding role of metformin in cancer: an update on antitumor mechanisms and clinical development.Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1.Combinational strategies of metformin and chemotherapy in cancers.Metformin and Prostate Cancer: a New Role for an Old Drug.Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation.Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells.Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L.Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells.Mechanisms of colitis-accelerated colon carcinogenesis and its prevention with the combination of aspirin and curcumin: Transcriptomic analysis using RNA-seq.Vorinostat and metformin sensitize EGFR-TKI resistant NSCLC cells via BIM-dependent apoptosis induction.Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells.Effects of metformin on the expression of AMPK and STAT3 in the spinal dorsal horn of rats with neuropathic pain.Metformin synergizes with rapamycin to inhibit the growth of pancreatic cancer in vitro and in vivo.Crucial microRNAs and genes in metformin's anti-pancreatic cancer effect explored by microRNA-mRNA integrated analysis.Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms.TGF-β1 mediates the effects of aspirin on colonic tumor cell proliferation and apoptosis.Pleiotropic Effects of Metformin on Cancer
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P2860
Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2
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2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Metformin combined with aspiri ...... totic proteins Mcl-1 and Bcl-2
@ast
Metformin combined with aspiri ...... totic proteins Mcl-1 and Bcl-2
@en
type
label
Metformin combined with aspiri ...... totic proteins Mcl-1 and Bcl-2
@ast
Metformin combined with aspiri ...... totic proteins Mcl-1 and Bcl-2
@en
prefLabel
Metformin combined with aspiri ...... totic proteins Mcl-1 and Bcl-2
@ast
Metformin combined with aspiri ...... totic proteins Mcl-1 and Bcl-2
@en
P2093
P2860
P921
P356
P1433
P1476
Metformin combined with aspiri ...... totic proteins Mcl-1 and Bcl-2
@en
P2093
Chung S Yang
Darren Carpizo
Huarong Huang
Robert S DiPaola
Xiang-Lin Tan
P2860
P304
21208-21224
P356
10.18632/ONCOTARGET.4126
P407
P577
2015-05-12T00:00:00Z