Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia.
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Epithelial Anion Transport as Modulator of Chemokine SignalingThe Contribution of the Airway Epithelial Cell to Host DefenseCFTR: a hub for kinases and crosstalk of cAMP and Ca2+Current progress of genetically engineered pig models for biomedical researchRibosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression DefectMechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blockerSynergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy.Mapping of long-range INS promoter interactions reveals a role for calcium-activated chloride channel ANO1 in insulin secretion.Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells.Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-β signaling.Quantitative proteomics reveals an altered cystic fibrosis in vitro bronchial epithelial secretomePotentiators of Defective ΔF508-CFTR Gating that Do Not Interfere with Corrector Action.New use for an old drug: COX-independent anti-inflammatory effects of sulindac in models of cystic fibrosis.Creation and characterization of an airway epithelial cell line for stable expression of CFTR variants.Cigarette smoke and CFTR: implications in the pathogenesis of COPDMechanism-based corrector combination restores ΔF508-CFTR folding and function.Correctors and Potentiators Rescue Function of the Truncated W1282X-Cystic Fibrosis Transmembrane Regulator (CFTR) Translation ProductThe secret life of CFTR as a calcium-activated chloride channel.Increased TMEM16A Involved in Alveolar Fluid Clearance After Lipopolysaccharide Stimulation.Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells.TMEM16A protein attenuates lipopolysaccharide-mediated inflammatory response of human lung epithelial cell line A549.Molecular, biophysical, and pharmacological properties of calcium-activated chloride channels.Differential Contribution of the Aryl-Hydrocarbon Receptor and Toll-Like Receptor Pathways to IL-8 Expression in Normal and Cystic Fibrosis Airway Epithelial Cells Exposed to Pseudomonas aeruginosa.Epithelial Chloride Transport by CFTR Requires TMEM16A.An unexpected effect of TNF-α on F508del-CFTR maturation and function.Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling.Recent insights into human bronchial proteomics - how are we progressing and what is next?Mutation-specific downregulation of CFTR2 variants by gating potentiators.Extracellular oxidation in Cystic Fibrosis airway epithelium causes enhanced EGFR/ADAM17 activity.The EGFR-ADAM17 Axis in Chronic Obstructive Pulmonary Disease and Cystic Fibrosis Lung Pathology.Molecular basis of cystic fibrosis: from bench to bedsideIdentification and Characterization of Novel CFTR Potentiators
P2860
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P2860
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Proinflammatory cytokine secre ...... fibrosis bronchial epithelia.
@ast
Proinflammatory cytokine secre ...... fibrosis bronchial epithelia.
@en
type
label
Proinflammatory cytokine secre ...... fibrosis bronchial epithelia.
@ast
Proinflammatory cytokine secre ...... fibrosis bronchial epithelia.
@en
prefLabel
Proinflammatory cytokine secre ...... fibrosis bronchial epithelia.
@ast
Proinflammatory cytokine secre ...... fibrosis bronchial epithelia.
@en
P2093
P2860
P356
P1476
Proinflammatory cytokine secre ...... fibrosis bronchial epithelia.
@en
P2093
A S Verkman
Florian Bossard
Gergely L Lukacs
Guido Veit
John W Hanrahan
Julie Goepp
Luis J V Galietta
P2860
P304
P356
10.1091/MBC.E12-06-0424
P577
2012-09-12T00:00:00Z