Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2 - Wikidata - awgldk - TriplyDB

Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2

Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2

http://www.wikidata.org/entity/Q36357354

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Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis Skin barrier homeostasis in atopic dermatitis: feedback regulation of kallikrein activity Ceramides stimulate caspase-14 expression in human keratinocytes.UVA-UVB photoprotective activity of topical formulations containing Morinda citrifolia extract The role of cathepsin E in terminal differentiation of keratinocytes.Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis.Increased matriptase zymogen activation in inflammatory skin disorders.Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage.Autosomal Recessive Congenital Ichthyosis in American Bulldogs Is Associated With NIPAL4 (ICHTHYIN) Deficiency.Protease-Activated Receptor-2 Is Associated with Terminal Differentiation of Epidermis and Eccrine Sweat Glands.Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function.T Helper 1 and T Helper 2 Cytokines Differentially Modulate Expression of Filaggrin and its Processing Proteases in Human Keratinocytes Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia: implications for the pathogenesis of psoriasis Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms "Outside-to-inside" (and now back to "outside") pathogenic mechanisms in atopic dermatitis.Impact on inflammation and recovery of skin barrier by nordihydroguaiaretic Acid as a protease-activated receptor 2 antagonist Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.Function of caspase-14 in trophoblast differentiation.Abnormalities in stratum corneum function in patients recovered from leprosy.Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia.Therapeutic Implications of a Barrier-based Pathogenesis of Atopic Dermatitis.Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis Genetic factors in susceptibility to contact sensitivity.A 3D self-organizing multicellular epidermis model of barrier formation and hydration with realistic cell morphology based on EPISIM.The Role of Interleukin-1 in Inflammatory and Malignant Human Skin Diseases and the Rationale for Targeting Interleukin-1 Alpha.Transcriptional gene silencing of kallikrein 5 and kallikrein 7 using siRNA prevents epithelial cell detachment induced by alkaline shock in an in vitro model of eczema.Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes.Analysis of gene expression dynamics revealed delayed and abnormal epidermal repair process in aged compared to young skin Risk factor-dependent dynamics of atopic dermatitis: modelling multi-scale regulation of epithelium homeostasis.Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis.Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair.Japanese Cedar (Cryptomeria japonica) pollen allergen induces elevation of intracellular calcium in human keratinocytes and impairs epidermal barrier function of human skin ex vivo.Tranexamic acid blocks the thrombin-mediated delay of epidermal permeability barrier recovery induced by the cedar pollen allergen, Cry j1

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Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2

http://www.wikidata.org/entity/Q36357354

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The American Journal of Pathology

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P2860

A proteolytic cascade of kallikreins in the stratum corneum

Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation

Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing

Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation

Basis for abnormal desquamation and permeability barrier dysfunction in RXLI

Expression and characterization of constitutively active human caspase-14

Cell death in the nervous system

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease

Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice

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