Deficient biosynthesis of N-acetylglucosaminyl-phosphatidylinositol, the first intermediate of glycosyl phosphatidylinositol anchor biosynthesis, in cell lines established from patients with paroxysmal nocturnal hemoglobinuria.
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Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A geneParoxysmal nocturnal hemoglobinuria from bench to bedsideBiosynthesis and deficiencies of glycosylphosphatidylinositolMetabolism of exogenous sn-1-alkyl-sn-2-lyso-glucosaminyl-phosphatidylinositol in HeLa D cells: accumulation of glucosaminyl(acyl)phosphatidylinositol in a metabolically inert compartmentExpression cloning of PIG-L, a candidate N-acetylglucosaminyl-phosphatidylinositol deacetylaseA case of paroxysmal nocturnal hemoglobinuria presenting with intra-abdominal bleeding due to splenic rupture, developing renal infarct.Molecules Great and Small: The Complement System.Leukemia arising out of paroxysmal nocturnal hemoglobinuria.Implications of recent insights into the pathophysiology of paroxysmal nocturnal haemoglobinuria.Historical aspects of paroxysmal nocturnal haemoglobinuria: 'defining the disease'.The mutational landscape of paroxysmal nocturnal hemoglobinuria revealed: new insights into clonal dominanceA new aspect of the molecular pathogenesis of paroxysmal nocturnal hemoglobinuria.Necrotizing Fasciitis in Paroxysmal Nocturnal Hemoglobinuria.A glycosylphosphatidylinositol (GPI)-negative phenotype produced in Leishmania major by GPI phospholipase C from Trypanosoma brucei: topography of two GPI pathways.Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria.A critical role for monocytes and CD14 in endotoxin-induced endothelial cell activation.Advances in the diagnosis and therapy of paroxysmal nocturnal hemoglobinuriaRecent developments in the understanding and management of paroxysmal nocturnal haemoglobinuria.Impaired growth and elevated fas receptor expression in PIGA(+) stem cells in primary paroxysmal nocturnal hemoglobinuriaSilencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma.Aurin tricarboxylic acid protects against red blood cell hemolysis in patients with paroxysmal nocturnal hemoglobinemia.The yeast spt14 gene is homologous to the human PIG-A gene and is required for GPI anchor synthesis.Anti-Complement Treatment in Paroxysmal Nocturnal Hemoglobinuria: Where we Stand and Where we are Going.Paroxysmal nocturnal hemoglobinuria and the age of therapeutic complement inhibition.The Pig-a Gene Mutation Assay in Mice and Human Cells: A Review.Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol anchor.Physiology and pathophysiology of complement: progress and trends.Biosynthesis of glycosylphosphatidylinositol membrane anchors.Clinical complementology: recent progress and future trends.The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes.The receptor for urokinase plasminogen activator is present in plasma from healthy donors and elevated in patients with paroxysmal nocturnal haemoglobinuria.Antibody selection against CD52 produces a paroxysmal nocturnal haemoglobinuria phenotype in human lymphocytes by a novel mechanismSuccessful use of eculizumab in an 86-year-old patient with paroxysmal nocturnal hemoglobinuria in JapanWhen pigs fly: immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis.Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents.Genotypic, immunophenotypic and clinical features of Thai patients with paroxysmal nocturnal haemoglobinuria.Quantitative dose-response analysis of ethyl methanesulfonate genotoxicity in adult gpt-delta transgenic mice.Fluorescent Aerolysin (FLAER)-based paroxysmal nocturnal hemoglobinuria (PNH) screening: a single center experience from India.Phenotypic and functional analysis of lymphocytes in paroxysmal nocturnal hemoglobinuria.
P2860
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P2860
Deficient biosynthesis of N-acetylglucosaminyl-phosphatidylinositol, the first intermediate of glycosyl phosphatidylinositol anchor biosynthesis, in cell lines established from patients with paroxysmal nocturnal hemoglobinuria.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Deficient biosynthesis of N-ac ...... smal nocturnal hemoglobinuria.
@ast
Deficient biosynthesis of N-ac ...... smal nocturnal hemoglobinuria.
@en
type
label
Deficient biosynthesis of N-ac ...... smal nocturnal hemoglobinuria.
@ast
Deficient biosynthesis of N-ac ...... smal nocturnal hemoglobinuria.
@en
prefLabel
Deficient biosynthesis of N-ac ...... smal nocturnal hemoglobinuria.
@ast
Deficient biosynthesis of N-ac ...... smal nocturnal hemoglobinuria.
@en
P2093
P2860
P356
P1476
Deficient biosynthesis of N-ac ...... smal nocturnal hemoglobinuria.
@en
P2093
M Takahashi
T Kinoshita
P2860
P304
P356
10.1084/JEM.177.2.517
P407
P577
1993-02-01T00:00:00Z